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goserelin |
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goserelin /go·se·rel·in/ (go´sĕ-rel″in) a synthetic gonadotropin-releasing hormone; on prolonged administration it suppresses release of gonadotropins and is used as the acetate salt to treat breast and prostate carcinomas and endometriosis and to thin the endometrium prior to endometrial ablation.
goserelin [go´sĕ-rel″in] a synthetic gonadotropin-releasing hormone; upon administration it initially stimulates release of follicle-stimulating hormone and luteinizing hormone and on prolonged administration later suppresses them. It is used as the acetate salt to treat breast and prostate carcinomas and endometriosis and to thin the endometrium prior to endometrial ablation; administered by subcutaneous implant. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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7) Goserelin was, however, associated with better relief of dyspareunia than the pill. By contrast, a study from the Austrian Breast and Colorectal Cancer Study Group (ABCSG) examined the role of bisphosphonates in premenopausal women treated with surgery and goserelin, and then randomly assigned to one of four treatment arms: tamoxifen, tamoxifen and ZA, anastrazole, or anastrazole and ZA. Contemporary therapies have varying mechanisms of action, including combined androgen blockage (gonadotrophin-releasing hormone agonist [eg, goserelin and leuprolide] combined with an androgen receptor antagonist [eg, flutamide, bicalutamide, and nilutamide]), gonadotrophin-releasing hormone antagonists (eg, abarelix), and 5[alpha]-reductase inhibitors (eg, finasteride and dutasteride). |
goserelin |
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