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gonadotropin-releasing hormone analogue

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gonadotropin-releasing hormone analogue
A polypeptide analogue of gonadotropin-releasing hormone–GnRH; some are more potent than GnRH in stimulating gonadotropin release Examples Leuprolide, histrelin, administered in a pulsatile fashion to restore lost GnRH, normalize pituitary-gonadal function, as in congenital GnRH deficiencies–eg, hypogonadotropic hypogonadism with Kallmann syndrome or without anosmia, or in acquired GnRH deficiency secondary to RT of the CNS, pituitary tumors, or panhypopituitarism. See Gonadotropin-releasing hormone.


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To initiate spawning, ripe females (mean oocyte diameter [greater than or equal to] 500 [micro]m) and males were implanted with a 75-[micro]g slow-release pellet of gonadotropin-releasing hormone analogue (Syndel International, Inc.
The topics include the secular trend of timing of puberty, the adrenal function of low-birthweight children, the molecular genetics of isolated hypogonadotropic hypogonadism and Kallmann syndrome, gonadotropin-releasing hormone analogue treatment for precocious puberty, polycycstic ovary syndrome in adolescence, and present and future options for preserving fertility in female adolescents with cancer.
 
 
 
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