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Hormone |
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hormone /hor·mone/ (hor´mon) a chemical substance produced in the body which has a specific regulatory effect on the activity of certain cells or a certain organ or organs.hormo´nal adrenocortical hormone 1. any of the corticosteroids elaborated by the adrenal cortex, the major ones being the glucocorticoids and mineralocorticoids, and including some androgens, progesterone, and perhaps estrogens. 2. corticosteroid. adrenocorticotropic hormone (ACTH) corticotropin. adrenomedullary hormones substances secreted by the adrenal medulla, including epinephrine and norepinephrine. androgenic hormone androgen. anterior pituitary hormones those produced in the adenohypophysis (anterior pituitary), including corticotropin, follicle-stimulating hormone, growth hormone, luteinizing hormone, prolactin, and thyrotropin. antidiuretic hormone vasopressin. cortical hormone adrenocortical h. corticotropin-releasing hormone (CRH) a neuropeptide elaborated mainly by the median eminence of the hypothalamus, but also by the pancreas and brain, that stimulates the secretion of corticotropin. ectopic hormone one released from a neoplasm or cells outside the usual source of the hormone. eutopic hormone one released from its usual site or from a neoplasm of that tissue. fibroblast growth hormone a peptide hormone secreted by the adenohypophysis that is a potent mitogen of vascular endothelial cells and a regulator of tissue vascularization. follicle-stimulating hormone (FSH) one of the gonadotropic hormones of the adenohypophysis; it stimulates ovarian follicle growth and maturation, estrogen secretion, and endometrial changes characteristic of the first portion of the menstrual cycle in females, and stimulates spermatogenesis in males. follicle-stimulating hormone–releasing hormone (FSH-RH) luteinizing hormone gonadotropic hormone gonadotropin. gonadotropin-releasing hormone (Gn-RH) 2. any hypothalamic factor that stimulates release of both follicle-stimulating hormone and luteinizing hormone. growth hormone (GH) any of several related hormones secreted by the adenohypophysis that directly influence protein, carbohydrate, and lipid metabolism and control the rate of skeletal and visceral growth; used pharmaceutically as somatrem and somatropin. growth hormone–releasing hormone (GH-RH) one elaborated by the hypothalamus, stimulating release of growth hormone from the adenohypophysis. inhibiting hormones hormones elaborated by one body structure that inhibit release of hormones from another structure; applied to substances of established clinical identity, while those whose chemical structure is still unknown are called inhibiting factors. interstitial cell–stimulating hormone luteinizing h. lactation hormone , lactogenic hormone prolactin. local hormone a substance with hormonelike properties that acts at an anatomically restricted site. luteinizing hormone (LH) a gonadotropin of the adenohypophysis, acting with follicle-stimulating hormone in females to promote ovulation as well as secretion of androgens and progesterone. It instigates and maintains the secretory portion of the menstrual cycle and is concerned with corpus luteum formation. In males, it stimulates the development and functional activity of testicular Leydig cells. luteinizing hormone–releasing hormone (LH-RH) a glycoprotein gonadotropic hormone of the adenohypophysis that acts with follicle-stimulating hormone to promote ovulation and promotes secretion of androgen and progesterone. A preparation of the salts is used in the differential diagnosis of hypothalamic, pituitary, and gonadal dysfunction and in the treatment of some forms of infertility and hypogonadism. melanocyte-stimulating hormone , melanophore-stimulating hormone (MSH) one of several peptides secreted by the anterior pituitary in humans and in the rhomboid fossa in lower vertebrates, influencing melanin formation and deposition in the body and causing color changes in the skin of amphibians, fishes, and reptiles. neurohypophysial hormones posterior pituitary h's. parathyroid hormone a polypeptide hormone secreted by the parathyroid glands, which influences calcium and phosphorus metabolism and bone formation. placental hormones those produced by the placenta during pregnancy, including chorionic gonadotropin and other substances having estrogenic, progestational, or adrenocorticoid activity. plant hormone phytohormone. posterior pituitary hormones those released from the neurohypophysis (posterior pituitary), including oxytocin and vasopressin. progestational hormone 1. progesterone. 2. see under agent. releasing hormones hormones elaborated in one structure that cause the release of hormones from another structure; applied to substances of established chemical identity, while those whose chemical structure is unknown are called releasing factors. somatotrophic hormone , somatotropic hormone growth h. somatotropin-releasing hormone (SRH) growth hormone steroid hormones those that are biologically active steroids; they are secreted by the adrenal cortex, testis, ovary, and placenta and include the progestogens, glucocorticoids, mineralocorticoids, androgens, and estrogens. thyroid hormones thyroxine, calcitonin, and triiodothyronine; in the singular, thyroxine and/or triiodothyronine. thyroid-stimulating hormone (TSH), thyrotropic hormone thyrotropin. thyrotropin-releasing hormone (TRH) a tripeptide hormone of the hypothalamus, which stimulates release of thyrotropin from the adenohypophysis and also acts as a prolactin-releasing factor. It is used in diagnosis of mild hyperthyroidism and Graves' disease, and in differentiating among primary, secondary, and tertiary hypothyroidism. A synthetic preparation is called protirelin.
Hormone Hormones are chemicals that are produced in an organ or gland and then are carried by the blood to another part of the body where they produce a special effect for which they were designed. Mentioned in: Acromegaly and Gigantism, Addison's Disease, Anabolic Steroid Use, Antidiabetic Drugs, Bone Disorder Drugs, Cholesterol-Reducing Drugs, Congenital Adrenal Hyperplasia, Corticosteroids, Cushing's Syndrome, Norplant, Drugs Used in Labor, Dysmenorrhea, Hormone Replacement Therapy, Human Chorionic Gonadotropin Pregnancy Test, Hypercalcemia, Hypophysectomy, IUD, Jet Lag, Kidney Disease, Menopause, Neuroblastoma, Oral Contraceptives, Pancreatitis, Pituitary Dwarfism, Puberty, Thyroid Hormones hormone (hōrˑ·mōn), n a chemical transmitter produced by endocrine glands. hormone(s) (hôr´mōn[z]), n.pl the biochemical secretions of the endocrine glands that, in relatively small quantities, partially regulate the physiologic activity of the tissues, organs, organ systems, and other endocrine glands, and of the nervous system itself. Its secretions are conducted and distributed throughout the body by the circulation of the bloodstream and tissue fluids. hormones, adenohypophyseal, n.pl the hormones secreted by the adenohypophysis. Includes seven distinct hormones: somatotropin (STH), thyrotropin (TSH), prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), melanocyte-stimulating hormone (MSH), and adrenocorticotropic hormone (ACTH). hormones, adrenal medullary, n.pl the hormones secreted by adrenal medulla, including two catecholamines: epinephrine and norepinephrine. hormones, adrenocortical, n the steroid hormones secreted by the adrenal cortex that are biologically active in one or more of the following states: stress, inflammation, metabolism of carbohydrates, proteins, electrolytes, and water. hormones, adrenocorticotropic, n See ACTH. hormones, adrenotropic, n See ACTH. hormones, anabolic, n.pl the hormones that decrease blood glucose; an example is insulin. See also anabolic steroids. hormones, androgenic, n.pl See hormones, sex, male. hormones, anterior pituitary-like, n See hormone, pregnancy. hormones, antidiabetic, n See insulin. hormones, antidiuretic (ADH, vasopressin), n a hormone of the posterior pituitary gland that encourages resorption of water by acting on the epithelial cells of the distal portion of the renal tubule. It raises blood pressure by its effect on the peripheral blood vessels and exerts an antidiuretic effect (antifacultative resorption of water in the renal tubules). An absence of antidiuretic hormone causes diabetes insipidus. hormones, antiinflammatory, n.pl See glucocorticoids. hormones, catabolic, n.pl the hormones that increase blood glucose; examples include glucagon, epinephrine, steroid and growth hormones, and thyroxine. hormones, chorionic gonadotropic, n a glycoprotein secreted by placental tissue early in normal pregnancy. This protein is also found in the urine or blood in association with chorioepitheliomas and some neoplastic diseases of the testes. hormones, corticosteroid, n See steroid, adrenocortical. hormones, corticotropic, n the ovarian or adrenal hormones (e.g., estradiol, estrone, estriol) that are capable of stimulating changes of a cyclic nature in the genital system. One of the ovarian or adrenal hormones capable of affecting the cyclic changes of the female genital system. See also ACTH. hormones, female sex, n.pl the hormones secreted by the ovary. They include two main types: the follicular, or estrogenic, hormones produced by the graafian follicle, and the progestational hormones from the corpus luteum. hormones, follicle-stimulating, a pituitary tropic hormone that promotes the growth and maturation of the ovarian follicle and, with other gonadotropins, induces secretion of estrogens and possibly spermatogenesis. hormones, gastrointestinal, n the hormones that regulate motor and secretory activity of the digestive organs; that is, gastrin, secretin, and cholecystokinin. hormones, gonadotropic, n See gonadotropin. hormones, growth (somatotropic hormone, somatotropin), n a hormone that is secreted by the anterior lobe of the pituitary gland and that exerts an influence on skeletal growth. As long as the growth apparatus is functional, it is responsive to the effects of the hormone. hormones, ketogenic, n the term used to describe a factor of the anterior pituitary hormone responsible for ketogenic effect. It is probably not an entity differing from known pituitary hormones. hormones, lactogenic (galactin, mammotropin, prolactin), n a pituitary hormone that stimulates lactation. hormones, luteal, n See hormones, progestational. hormones, luteinizing, n a pituitary hormone that causes ovulation and development of the corpus luteum from the mature graafian follicle. It is called an interstitial cell and stimulating hormone because of its action on the testis in maintaining spermatogenesis and because of its role in the development of accessory sex organs. hormones, male sex (androgenic hormone, C-19 steroids), n.pl the hormones found in the testes, urine, and blood. Included are testosterone found in the testes, andosterone excreted into the urine, and dehydro-3-epiandrosterone found in the blood. hormones, melanocyte-stimulating (MSH, intermedin), n a hormone of the middle lobe of the pituitary gland that increases melanin deposition by the melanocytes of the skin. hormones, N, n See hormone, nitrogen and steroid, C-19 cortico. hormones, neurohypophyseal, n.pl the octapeptides of the neural lobe: oxytocin and vasopressin. hormones, nitrogen (N hormone), n.pl the C-19 corticosteroids that have androgenic and protein anabolic effects. hormones, parathyroid, n the secretory product of the parathyroid glands that promotes bone resorption and increases renal resorption of calcium and magnesium and diminishes that of phosphate. Excessive secretion produces generalized bone resorption, formation of fibrous marrow in the spongiosa, and, in young individuals, hypocalcification of the teeth. hormones, pituitary, n.pl the hormones of the anterior lobe of the pituitary gland, including the growth hormones (somatotropin 1, lactogenic hormone, prolactin, galactin, mammotropin) and pituitary tropins (gonadotropins, thyrotropic hormone, and ACTH). Whether or not a true diabetogenic pituitary hormone exists is a question. The melanocyte-stimulating hormone is secreted by the middle lobe of the pituitary gland, and vasopressin and oxytocin are secreted by the posterior lobe of the pituitary gland. hormones, pregnancy (anterior pituitary-like hormone, antuitrin S, chorionic gonadotropin), n a gonadotropic hormone found in the urine during pregnancy; it is a product of the very early placenta. hormones, progestational (luteal hor-mone), n.pl the hormones produced during the phase of the menstrual cycle just preceding menstruation. Includes progesterone, pregnanediol, and pregneninolone. hormones, proinflammatory, n See mineralocorticoids. hormones, “S” (glucocorticoid factor, sugar hormone), n a factor in the secretions of the adrenal cortex related to the regulation of carbohydrate metabolism. hormones, sex, n.pl the steroid hormones that are produced by the testes and ovaries and that control secondary sex characteristics, the reproductive cycle, development of the accessory reproductive cycle, and development of the accessory reproductive organs. Also included are the gonadotropins produced by the pituitary gland. hormones, somatotropic, n See hormone, growth. hormones, steroid, n.pl a group of biologically active organic compounds that are secreted by the adrenal cortex, testes, ovary, and placenta, and that have in common a cyclopentanoperhydrophenanthrene nucleus. hormones, sugar, n See hormone, “S” and steroid, C-21 cortico-. hormones, testicular, n.pl the hormones elaborated by the testes (mainly testosterone) that promote the growth and function of the male genitalia and secondary sex characteristics and that have potent protein anabolic effects. hormones, thyroid, n.pl the hormonal variants, including thyroxin and triiodothyronine, derived from the thyroid gland. They act as a catalyst for oxidative processes of the body cell and thus regulate the rates of body metabolism and stimulate body growth and maturation. hormones, thyroid, thyroid-stimulating, n See hormone, thyrotropic. hormone a chemical transmitter substance produced by cells of the body and transported by the bloodstream and other means to the cells and organs which carry specific receptors for the hormone and on which it has a specific regulatory effect. Hormones act as chemical messengers to body organs, stimulating certain life processes and retarding others. Growth, reproduction, control of metabolic processes, sexual attributes and behavior are dependent on hormones. Hormones are produced by various organs and body tissues, but mainly by the endocrine glands, such as the pituitary, thyroid and gonads (testes and ovaries). Each gland apparently manufactures several kinds of hormones; the adrenal glands alone produce more than 25 varieties. The total number of hormones is still unknown, but each has its unique function and structure. After a hormone is discharged by its parent gland into the capillaries or the lymph, it may travel a circuitous path through the bloodstream to exert influence on cells, tissues and organs (target organs) far removed from its site of origin. adrenomedullary h's substances secreted by the adrenal medulla, including epinephrine and norepinephrine. androgenic h's the masculinizing hormones, androstenedione and testosterone. hormone assay modern techniques include the use of competitive protein binding assay and radioimmunoassay. calciotropic hormone any hormone which is specifically involved in the homeostatic regulation of serum calcium levels through their effects on bone and other organs, e.g. parathyroid hormone, calcitonin. corpus luteum hormone progesterone. cortical hormone corticosteroid. ectopic h's those secreted by tumors of nonendocrine tissues but having the same physiological effects as their normally produced counterparts. It is not known exactly how the synthesis and secretion of endocrine hormones from nonendocrine tissues occurs. Most of these tumors are derived from tissues that have a common embryonic origin with endocrine tissues. When the cells undergo neoplastic transformation, they can revert to a more primitive stage of development and begin to synthesize hormones. enteric hormone hormone secreted by endocrine cells in the wall of the intestine or stomach or in the pancreas. Includes gastrin, cholecystokinin, secretin, gastric inhibitory polypeptide, enteroglucagon, motilin, neurotensin, 5-HT, substance P, pancreatic polypeptide, somatostatin. estrogenic h's substances capable of producing certain biological effects, the most characteristic of which are the changes which occur in mammals at estrus; the naturally occurring estrogenic hormones are ß-estradiol, estrone and estriol. gonadal h's steroids in birds which affect development of the reproductive tubular system, head decorations, feathers, squawk, behavior. hormone herbicide substances sprayed on plants which exert a lethal hormonal effect on the entire plant. See also hormone weedkiller (below). lactation hormone, lactogenic hormone prolactin. luteotropic hormone (LTH) see luteotropin. neurohypophyseal h's those stored and released by the neurohypophysis, i.e. oxytocin and vasopressin. peptide h's peptide molecules which exert their effects only on target cells that carry the hormone-specific receptors. placental hormone one secreted by the placenta, including chorionic gonadotropin, relaxin, and other substances having estrogenic, progestational or adrenocorticoid activity. See also placental hormones. progestational h's substances, including progesterone, that are concerned mainly with preparing the endometrium for nidation of the fertilized ovum if conception has occurred. See also progestational agent. hormone receptors the presence of hormone-specific receptors on cells is the means of determining which cells respond to the circulating hormones. The number of receptors on each cell is one of the ways of regulating the degree of response. reproductive h's sex h's see sex hormones. somatotrophic hormone, somatotropic hormone growth hormone. somatotropin release inhibiting hormone somatostatin. somatotropin releasing hormone (SRH) growth hormone releasing hormone. thymic hormone thymosin. hormone adjective Referring to a hormone, hormonal noun Endocrinology A chemical messenger produced in an endocrine gland and released into the circulation to effect a change in a specific target organ; hormones regulate the internal environment, effecting homeostatic control, regulate reproductive processes, and affect mood and behavior Types Steroid hormones–cortisol, estrogen, testosterone; nonsteroid hormones–choleckystokinin, epinephrine, dopamine, insulin, norepinephrine, serotonin, vasopressin. See ACTH, Beef growth hormone, Biological thyroid hormone, Candidate hormone, Designer hormone, Ectopic hormone, Emasculated hormone, Fat mobilizing hormone, FSH, Gonadotropin-releasing hormone, Growth hormone, HCG, LH, LH-RH, Melanocyte-stimulating hormone, Neurohormone, Pheromone, PTH, Somatotropin release-inhibiting hormone, Thyrotropin releasing hormone, TSH. Cf Neurotransmitter. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In male FHMs, trenbolone-[beta] could act at the level of the hypothalamus of pituitary to depress gonadotropin-releasing hormone (GnRH) and/or gonadotropic hormone (GtH) synthesis and/or release, leading to decreased T synthesis, testicular mass, and IO distance, as was seen in this study in the males from the contaminated site. The LHRH agonist, a Roberts therapeutic, is a synthetic gonadotropic hormone releasing factor agonist that, due to its long-term inhibition of pituitary release of gonadotropins, can block both ovarian and testicular function. |
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