gonadoblastoma

gonadoblastoma

[gō′nədōblastō′mə]

Etymology: Gk, gone, seed + blastos, germ + -oma, tumor

a rare benign type of germ cell tumor, usually occurring in patients with gonadal dysgenesis, and often bilateral. It contains all gonadal elements and is frequently associated with an abnormal chromosomal karyotype. It may give rise to a dysgerminoma or other more malignant germ cell tumor. See also dysgerminoma, gonadal dysgenesis.

---

gonadoblastoma

a rare, primary tumor of testicle or ovary containing, besides interstitial cells, germ cells, epithelial cells and granulosa cells.

---

gonadoblastoma

Gynecology Dysgenetic gonadoma A mixed germ cell-sex cord-stromal tumor which is most commonly seen in sexually abnormal persons, especially with gonadal dysgenesis–GD with a Y chromosome–ie, XY GD and XO-XY mosaicism; gonadoblastomas carry a 25% risk of neoplasia. See Sex-cord tumor Urology A mixed germ cell-sex cord-stromal tumor which almost invariably arises in a background of a gonadal disorder, either pure or mixed gonadal dysgenesis, male pseudohermaphroditism or, less commonly, in a phenotypically or karyotypically normal male. See Sex cord-stromal tumor.