gold sodium thiomalate

gold (Au) (gōld) a chemical element, at. no. 79; gold compounds (all of which are poisonous) are used in medicine, chiefly in treating arthritis.

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gold 198  a radioisotope of gold with a half-life of 2.69 days; it has been used as an intracavitary and interstitial antineoplastic and as a scintiscanning agent.

cohesive gold  chemically pure gold that forms a solid mass when properly condensed into a tooth cavity.

gold sodium thiomalate  a monovalent gold salt used in treatment of rheumatoid arthritis.

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gold sodium thi·o·mal·ate (th-mlt, -mlt)

n.

An intravenous drug containing two salts of the element gold, used to treat rheumatoid arthritis.

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gold sodium thiomalate,

an antirheumatic.

indication It is prescribed for the treatment of rheumatoid arthritis.

contraindications Severe debilitation, systemic lupus erythematosus, renal or liver disease, blood dyscrasias, Sjögren's syndrome (in rheumatoid arthritis), or known hypersensitivity to this drug or to other gold or heavy metal salts prohibits its use.

adverse effects Among the most serious adverse effects are various blood dyscrasias, renal damage, and allergic reactions. Dermatitis, stomatitis, and lesions of the mucous membranes also may occur.

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gold (Au) [gōld]

chemical element, atomic number 79, atomic weight 196.967. (See Appendix 6.) Gold and many of its compounds are used in medicine, especially in treating rheumatoid arthritis. Gold salts are among the most toxic of therapeutic agents and must be given only under strict medical supervision. Toxic reactions may vary from mild to severe kidney or liver damage and blood dyscrasias.

gold 198 a radioisotope of gold having a half-life of 2.7 days, used as either a solid (seed) or a colloidal solution. It has been used for intracavitary or interstitial radiation therapy and has also been used, in colloidal form, as a scintiscanning agent. Symbol ¹⁹⁸Au.

gold sodium thiomalate a gold preparation used as a disease-modifying antirheumatic drug in treatment of early active rheumatoid arthritis not controlled by nonsteroidal antiinflammatory drugs, rest, and physical therapy; administered intramuscularly.