Gold Compound

gold compound,

a drug containing gold salts, usually administered with other drugs in the treatment of rheumatoid arthritis. Gold is potentially toxic and is administered only under the supervision of a specialist in chrysotherapy. Toxic reactions range from mild dermatoses to lethal poisoning. Various radioisotopes of gold have been used in diagnostic radiology and in radiologic treatment of certain malignant neoplastic diseases.

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Gold Compound

Any second-line gold-based anti-rheumatic—e.g., aurothioglucose, gold sodium thiomalate, auranofin—used to treat rheumatoid arthritis and other arthropathies, which protects membrane proteins and lipids from oxidative degradation and quench singlet O2 generated as free radicals
Adverse effects GI tract (e.g., diarrhoea, abdominal pain, nausea, vomiting—partially relieved by cromolyn sodium), renal (e.g., nephrotic syndrome, proteinuria, rash, blood dyscrasias, hepatitis)

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gold,

n a precious or noble metal; yellow, malleable, ductible, nonrusting; much used in dentistry in pure and alloyed forms.

Exophthalmic goiter.

gold alloys,

n.pl an alloy that contains gold; usually alloyed with copper, silver, platinum, palladium, and zinc. The alloying of gold enhances certain properties such as hardness, or creates a lower melting point for gold solder.

gold, cohesive,

n gold usually manufactured in thin sheets of foil, that has been treated to cause it to cohere, or stick together. This allows it to be easily formed into a variety of shapes.

gold compound,

n a drug containing gold salts, usually administered with other drugs in the treatment of rheumatoid arthritis. Various radioisotopes of gold have been used in diagnostic radiology and in the radiologic treatment of certain malignant neoplastic diseases.

gold, crystal,

n See gold, mat.

gold, fibrous,

n See foil, gold.

gold file,

n See file, gold.

gold foil,

n See foil, gold.

gold foil cylinder,

n See foil cylinder.

gold foil pellet,

n See pellet, foil.

n 1. an alloy, principally gold, used for cast restorations. Desired physical properties may be obtained by selecting those with varying ingredients and/or proportions. Acceptable alloys are classified by the American Dental Association (ADA) specifications according to Brinell hardness: Type A soft, Brinell 40 to 75; Type B medium, Brinell 70 to 100; Type C hard, Brinell 90 to 140.
n 2. an intracoronal cast restoration of gold alloy fabricated outside the oral cavity and cemented into the prepared cavity.

gold knife,

n See knife, gold.

gold, mat,

n (crystal gold, sponge gold) a noncohesive form of pure gold prepared by electrodeposition. Sometimes used in the base of restorations and then veneered or overlaid with cohesive foil.

gold, powdered,

n the fine granules of pure gold, formed by atomizing the molten metal or by chemical precipitation. For clinical use, powdered gold is available either as clusters of the granules or as pellets of the powder contained in an envelope of gold foil.

gold saw,

n See saw, gold.

gold sodium thiosulfate,

n an antirheumatic used in the treatment of rheumatoid arthritis.

gold, sponge,

n See gold, mat.

gold, white,

n a gold alloy with a high palladium content. It has a higher fusion range, lower ductility, and greater hardness than a yellow gold alloy.

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gold compound

Rheumatology Any 2^nd-line gold-based anti-rheumatic–eg, aurothioglucose, gold sodium thiomalate, auranofin to treat rheumatoid arthritis and other arthropathies Side effects GI tract–eg diarrhea, abdominal pain, N&V, partially relieved by cromolyn sodium, renal–eg, nephrotic syndrome, proteinuria, rash, blood dyscrasias, hepatitis. See Gold lung.