goblet cell carcinoid

goblet cell carcinoid (appendix)

A type of mixed endocrine/exocrine neoplasm with both endocrine and glandular differentiation.

Clinical findings
GCCs are more aggressive than classic carcinoid tumours, and behave as low-grade malignancies.
References in periodicals archive ?
Goblet cell carcinoid of the appendix: endoscopically diagnosed and examined with p53 immunostaining.
Goblet cell carcinoid of the appendix as a distinct entity was first described in 1974.
Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix.
Among the unusual variants of carcinoid tumors reported to SEER, 5 were goblet cell carcinoids, which are more common in the appendix, (40) and 2 were somatostatin-producing carcinoids, which usually show a glandular pattern.
9,10) In contrast, goblet cell carcinoid tumors of the appendix are rare, and they have a mixed phenotype with partial neuroendocrine differentiation and intestinaltype goblet cell morphology.
17-19) A mucin stain may be used, in some cases, for the differential diagnosis with a goblet cell carcinoid (see below).
Goblet cell carcinoids (GCCs; synonymous terms: adenocarcinoids, goblet cell tumors) have mixed phenotypes, with partial neuroendocrine differentiation and intestinal goblet cell morphology.
Dr Laura Tang addresses tumors of the appendix, focusing on mucinous neoplasms and the spectrum of neuroendocrine tumors, including goblet cell carcinoid tumor.
Appendiceal goblet cell carcinoid (GCC) is rare, with a significantly higher metastatic rate than the conventional appendiceal carcinoid.
According to Stancu and colleagues, goblet cell carcinoids did not show mutations in SMAD4 (18).
Goblet cell carcinoids, poorly differentiated carcinomas with neuroendocrine features, and small cell carcinomas are not included.