gnotobiotic


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gno·to·bi·ot·ic

(nō'tō-bī-ot'ik),
Denoting germ-free or formerly germ-free organisms in which the composition of any associated microbial flora, if present, is fully defined.
[see gnotobiota]

gnotobiotic

[nō′tōbī·ot′ik]
pertaining to a germ-free animal or an animal or an environment in which all the microorganisms are known. See also germ-free animal.

gnotobiotic

Biology
adjective Referring to a system to which only preselected components, organisms and nutrients are introduced. Gnotobiotic organisms are either experimental models (e.g., mice with naïve immune systems), or “experiments of nature”, in which the natural immune defence is grossly defective (e.g., severe combined immune deficiency); prolonged survival of the host requires complete avoidance of exposure to pathogens.

gno·to·bi·ot·ic

(nō'tō-bī-ot'ik)
Denoting germ-free or formerly germ-free organisms in which the composition of any associated microbial flora, if present, is fully defined.

gnotobiotic

literally ‘known life’; typically referring to an environment or animal that is essentially germ-(microorganism-) free, or one in which the microbial flora present is known, usually because it has been deliberately introduced.

gnotobiotic

pertaining to a gnotobiote or to gnotobiotics.

gnotobiotic animal
one that has been born germ free and then infected with known microorganisms. See also axenic and specific pathogen free.
References in periodicals archive ?
To this end, we compared gnotobiotic mice associated with several microbial preparations derived from various origins with or without chloroform treatment.
Effects of microbiota on GI health: gnotobiotic research.
Epithelial attachment and other factors controlling the colonization of the intestine of the gnotobiotic chicken by lactobacilli.
Table 4: Plant growth promotion of wheat seedlings under drought (No PEG, 15 and 25% PEG) when inoculated with Mesorhizobium ciceri isolated from chickpea nodules in gnotobiotic conditions
Using pathogen-free mice, germ-free mice, and gnotobiotic mice, the authors determined the catecholamine levels in the gastrointestinal tract of these mice.
To demonstrate this point, investigators conducted experiments in which they transplanted the gut microbiota of either ob/ob mice or lean mice to lean gnotobiotic mice.
Our gnotobiotic methodologies have allowed us to infer the roles that the resident microbiota play in host development by comparing the traits of germ-free and conventionally reared zebrafish (Bates et al.
Gnotobiotic assay or growth pouch study (GPS) with maize revealed that with control experiment less amount of IAA production were recorded (0.
Today, gnotobiotic animals are used in labs around the world (6/18/11, p.
Experimental study of the pathogenicity of Neoaplectana carpocapsae: Gnotobiotic studies in Galleria mellonella.
putida GR 12-2 strain have this ability to develop the root length of canola seedlings under the gnotobiotic conditions.
Enteropathogenic Escherichia coli enteritis: evaluation of the gnotobiotic piglet as a model of human infection.