glyoxalase


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gly·ox·a·lase

(glī-oks'ă-lās),
An enzyme, lactoylglutathione lyase (g. I) or hydroxyacylglutathione hydrolase (g. II), in erythrocytes and other tissues that converts glyoxal and substituted glyoxals bound to glutathione into the corresponding free hydroxy acids (g. II) or glyoxals (g. I).

glyoxalase

(glē-ōk′să-lās)
An enzyme that catalyzes the conversion of methylglyoxal to lactic acid by the addition of water.
References in periodicals archive ?
In addition, paeoniflorin increased glutathione level and restored the activity of glyoxalase I to almost the control level.
D-lactate is generated by degradation of methylglyoxal, an intermediate glucose metabolite, through the glyoxalase system (3, 5).
of the University's Center for Drug Design, found evidence that a lab-made compound known as psi-GSH enables the brain to use its own protective enzyme system, called glyoxalase, against the Alzheimer's disease process.
DA also stopped a protective protein called glyoxalase I from safeguarding nerve cells.
The volume opens with overview chapters on dehydration tolerance, salinity tolerance, cold stress acclimation, redox-dependent regulation and oxidative damage in plants subjected to abiotic stress, array platforms and bioinformatic tools for the analysis of plant transcriptome in response to stress, and metabolic engineering of glyoxalase pathways for enhancing stress tolerance in plants.
First, we found that an increase in polarity of glyoxalase I in autism brains was reported and that glyoxalase system involves also lactoylglutathione.
Modification of the glyoxalase system in disease processes and prospects for therapeutic strategies.
His research group utilizes recombinant DNA, biophysical and organic synthetic techniques to explore the enzymes involved in methionine salvage pathways, various methyltransferases and the enzyme glyoxalase I.