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glycosylation

   Also found in: Wikipedia 0.04 sec.
glycosylation /gly·co·syl·a·tion/ (gli-ko?si-la´shun) the formation of linkages with glycosyl groups.
gly·co·sy·la·tion (glk-s-lshn)
n.
The addition of glycosyl groups to a protein to form a glycoprotein.
glycosylation (glī·kōˈ·s·lāˑ·shn),
n process in which a carbohydrate is covalently attached to another molecule.
glycosylation
the formation of linkages with glycosyl groups.
N-linked glycosylation
attachment of oligosaccharides, synthesized on a dolichol-lipid platform to proteins through the amino acid asparagine spaced close to threonine or serine in the polypeptide sequence.
O-linked glycosylation
attachment of groups of oligosaccharides directly to proteins through the hydroxyl group of threonine.
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If one assumes that the PrPres glycosylation process could be similar in classic (+3.
Similar biochemical signatures and prion protein genotypes in ... by Baron, Thierry / Emerging Infectious Diseases
MX-3253 (celgosivir) is an alpha-glucosidase I inhibitor and is currently the only oral anti-HCV drug in clinical development that acts through host- directed glycosylation.
MIGENIX INITIATES ENROLLMENT IN PHASE IIB HEPATITIS TRIAL by Worldwide Biotech
Recently, however, mutations that result in altered glycosylation of [alpha]-dystroglycan have been reported to be linked to both murine (40) and human MDs, (41,42) including muscle-eye-brain disease, Walker-Warburg syndrome (WWS), and a type of congenital MD (MDC1D).
The muscular dystrophies: from genes to therapies by Bloch, Robert J. / Physical Therapy
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