GPM6A

(redirected from glycoprotein M6A)

GPM6A

A gene on chromosome 4q34 that encodes a multipass membrane protein involved in neuronal differentiation, migration of neuronal stem cells, neuronal plasticity, filopodia motility and probably synapse formation. It may be involved in neuronal NGF-dependent Ca2+ influx, regulating endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), and in enhancing internalisation and recycling of mu-type opioid receptors.