glycoprotein IIb

glycoprotein IIb/IIIa

a transmembrane protein of platelets, an integrin that binds fibrinogen, von Willebrand's factor, and other adhesive ligands and plays a role in platelet aggregation and thrombus formation.
References in periodicals archive ?
4] Human genes: ITGA2B, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGBB3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61).
63) Mutations of both glycoprotein IIb and glycoprotein IIIa have been implicated.
Topics covered include the use of aspirin for primary and secondary prophylaxis, the role of platelet inhibitors and glycoprotein IIb and IIIa inhibitors, pentasaccharides, warfarin, and other agents.
They often aggressively pile on short-term use of multiple antiplatelet agents, antithrombins, and / or glycoprotein IIb /IIIa inhibitors in addition to moderate- or high-dose aspirin in an effort to minimize the risk of subacute thrombosis in conjunction with stenting.