glycophorin


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glycophorin

 [gli″ko-for´in]
any of several related proteins that can project through the thickness of the cell membrane of erythrocytes; they attach to oligosaccharides at the outer cell membrane surface and to contractile proteins (spectrin and actin) at the cytoplasmic surface.

glycophorin

/gly·co·phor·in/ (-for´in) any of several related proteins that can project through the thickness of the cell membrane of erythrocytes; they attach to oligosaccharides at the outer cell membrane surface and to contractile proteins (spectrin and actin) at the cytoplasmic surface.

glycophorin

[-fôr′in]
one of a group of proteins (A-E) that project through the membrane of red blood cells (RBCs). The outside end of glycophorins A and B carries antigens of the MNS blood group. The sialic acid component of glycophorins contributes to the negative charge of the outer erythrocyte plasma membrane. Influenza virus can attach to sialic acid present on glycophorin A, B, C, D, and E and produce agglutination (does not enter RBCs). Malaria virus can attach to glycophorin A and C and infect RBCs. See also blood group.

glycophorin

a glycopolypeptide found in human erythrocytes.

glycophorin

a protein that projects through the thickness of the cell membrane of erythrocytes; it is attached to oligosaccharides at the outer cell membrane surface and to contractile proteins (spectrin and actin) at the cytoplasmic surface.
References in periodicals archive ?
Tenders are invited for Supply of IHC Antibodies, Chromogranin 6-7ml vial, Synaptophysin 6-7ml vial, P63 6-7ml vial, Thyroglobulin 6-7ml vial, Glycophorin A 3-4ml vial, EBV-LMP-1 3-4ml vial etc.
Phycoerythrin (PE)-labeled monoclonal antibody against human glycophorin A (anti-glycophorin A-RPE) was from Dako (Glostrub, Denmark), and fluo-4 acetoxymethyl ester (Fluo-4 AM) was from Molecular Probes (Eugene, OR, USA).
The most common cause is infection with parvovirus type B19, which infects early erythroid precursors through the glycophorin receptor.
They found that the EBA175 protein from chimpanzee specific malaria parasites could bind to human Glycophorin A, thereby ruling out this interaction as a specificity factor.
We assayed the correlation between gene expression levels of VEGF-A or VEGF-C and expression of antigens CD2, CD3, CD4, CD7, CD10, CD11b, CD13, CD14, CD15, CD19, CD20, CD22, CD33, CD34, CD38, CD45, HLA-DR, TdT, and glycophorin A; no significant correlations were found.
The replaced amino acids were located in a refined 3-dimensional computer model of the HAV protomer (11), and their relative distances to residues 1102, 1171 and 1176, constituents of the immunodominant site (12), and to residue 1221, constituent of the glycophorin A binding site epitope (13), were used as markers of the potential antibody-escaping phenotype.
Moderate to bright expression of CD71 (transferrin receptor) and glycophorin A (CD235a) provides evidence of erythroid differentiation, but it should be noted that dim expression of the former is seen on many activated cell types, including neoplastic myeloblasts.
XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency.
Glycophorin A, for example, is a heavily glycosylated protein present on the surface of human erythrocytes.
Because RII binds on the red blood cell to glycophorin A, a protein with numerous sugar chains, the researchers determined the atomic structure of RII crystallized alone and with sugar molecules called glycans.
The cells stained with CD31 (figure, B) and glycophorin, which indicated the presence of a mixture of megakaryocytic and erythroid cells.
Still others, including David Aminoff of the University of Michigan at Ann Arbor, contend red-cell aging is accompanied by a loss of sialic acid residues from a membrane protein called glycophorin.