glycopeptides

glycopeptides

[-pep′tīdz]
a class of peptides that contain sugars linked with amino acids, as in bacterial cell walls.
References in periodicals archive ?
ProtoKinetix has developed and patented a family of hyper stable, potent glycopeptides that enhance both engraftment and protection of transplanted cells used in regenerative medicine.
Dardi Charan Kaur et al also observed that none of their 36 isolates were resistant to antimicrobial category like glycopeptides, glycylcyclines and fucidanes.
4),(5) S-glycosylation is rare, and only observed in glycopeptides.
We applied our previously reported affinity-chromatography method in combination with a bottom-up proteomics approach comprising an enzymatic deglycosylation scheme to retain a small glycan moiety attached to the glycopeptides as direct proof of glycosylation, single as well as combined enzymatic protein digestion, [beta]-elimination with concomitant Michael addition chemistry, and high-resolution nano-LC-MS (3, 23, 24).
Evaluation of current methods for detection of staphylococci with reduced susceptibility to glycopeptides.
The various classes of antibacterial drug included in this report are beta-lactams, macrolides, aminoglycosides, phenicols, quinolones, folate antagonists, tetracyclines, and other miscellaneous agents, which include glycopeptides, nitroimidazoles, lincosamides, lipopeptides, nicotinic acid derivatives, and polypeptide antibiotics.
Enterococci are the third most common bacteriae isolated in nasocomial infections in USA and in bloodstream infections in developed countries and a gradual increase in resistance especially to glycopeptides has become an important problem in recent years (14, 15).
62/007,626 related to the use of anti-aging glycopeptides to enhance beta cell health, survival and improve transplant outcomes, and all patents issuing from and claiming priority to such application.
ProtoKinetix has developed and patented a family of hyper stable, potent glycopeptides (AAGP) that (it says) enhance the therapeutic results and reduce the cost of stem cell medicine.
The choice was based on local policy: aminoglycosides (amikacin and gentamycin), semi-synthetic penicillin with beta-lactamases inhibitor (ampicillin/sulbactam), third and fourth generation of cephalosporins (ceftriaxone, ceftazidime and cefepime), fluoroquinolones (ciprofloxacin and levofloxacin), ureidopenicillin with beta-lactamase inhibitor (piperacillin/tazobactam), glycopeptides (vancomycin and teicoplanin), polymyxin, carbapenems (meropenem and imipenem) and tetracyclines (tigecycline).
Many of these MRSA isolates are becoming multidrug resistant and are susceptible only to glycopeptides antibiotics such as vancomycin & teicoplanin.