GSK3B

(redirected from glycogen synthase kinase 3 beta OTTHUMP00000165240 GSK-3 beta)

GSK3B

A gene on chromosome 3q13.3 that encodes a serine-threonine kinase of the glycogen synthase kinase subfamily, which is involved in glycogen metabolism, proliferation, motility, survival, neuronal development and body pattern formation.
 
Molecular pathology
GSK-3 plays a role in diabetes, cancer and neurologic disease—GSK3B polymorphisms are implicated in Parkinson disease; GSK3B overexpression may play a role in Alzheimer’s disease.
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