Dr Sharad Purohit, co-investigator and author, said, "Proteins determine cell function and about half the proteins we make are modified by glycans
in a continuous and fundamental biochemical process".
In this study, a lectin microarray was used to investigate the glycan
profile of urinary proteins between DN and NDRD patients.
The problem, however, is that while the human immune system wants to produce antibodies that bind to the glycoprotein, a shield of sugar molecules called glycans
block immune cells from seeing their targets and developing useful antibodies.
analyses can rarely be performed on the intact glycoprotein.
A novel protein glycan
biomarker and LCAT activity in metabolic syndrome.
However, the good news for those who have an older biological age is that tests indicate that you can restore a younger pattern of glycans
, simply by overhauling your lifestyle.
Scientists say there is the potential to target these glycans
which could stop the growth and spread of tumours and save lives.
Using this platform along with a mass spectrometer, BTI's researchers can apply their expertise in the production of therapeutic glycoproteins to develop optimized workflows and methods for the analysis of N- and O- linked glycans
Midatech is applying its glycan
coated gold nanoparticle (GNP) technology platform to the treatment of diabetes, a range of orphan oncology indications including brain, liver, pancreatic and ovarian cancer and neurological/ophthalmologic conditions, most of which have multi-$100 million or multi-$billion markets.
labeling kits; glycan
purification kits; glycan
release kits; and other glycomics kits are subsegments of the kits market.
Matthew Macauley, a senior research associate in Paulson's group, and colleagues treated the animals with tiny nanoparticles that included both Factor VIII and the glycan
that binds with CD22.
Scientists are attempting to develop production and processing models that recognize the intrinsic biological value of food byproducts and sidestreams, which may contain these glycans