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glutathione conjugation

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glutathione conjugation,
n a phase II detoxification reaction in the liver; glutathione combines with toxins and converts them into water-soluble mercaptates. Effectively detoxifies acetaminophen and nicotine.


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Glutathione conjugation is the chemical that is responsible for making this happen.
However, there are a number of metabolites of potential toxicologic interest, such as chloral, dichloroacetic acid (DCA), or those derived from glutathione conjugation, for which reliable data are sparse because of analytical difficulties or low concentrations in systemic circulation.
 
 
 
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