Biochemical characterization of a novel L-asparaginase With low glutaminase
activity from Rhizomucor miehei And its application in food safety and leukemia Treatment.
producers, Escherichia and Bacillus spp.
According to the company, its lead product candidate, CB-839, is a potent, selective, reversible and orally bioavailable inhibitor of glutaminase
Dexamethasone administration induces increased glutaminase
specific activity in the jejunum and colon.
catalyses the conversion of L-glutamine to glutamate, an important component of taste and quality in food, and it could be used as an alternative to other processes to produce high glutamate foods or ingredients, Mr McCutcheon said.
Ochi, "Diphenylarsinic acid promotes degradation of glutaminase
C by mitochondrial Lon protease," The Journal of Biological Chemistry, vol.
9 Ischaemia modifies Gln metabolism resulting in over-activity of Glnsynthetase causing increased production and a relative inactivity of glutaminase
enzyme responsible for Gln clearance.
coli LPS) may be due to metabolic stress processes during which there is a reduction in luminal transport of glutamine and in the activity of the mucosal glutaminase
(19), with the possibility of the intestine meeting the needs of other organs as part of the process for prioritizing protein synthesis and thus not compromising the use of nutrients.
This enzyme is an exopeptidase with endopeptidase and glutaminase
Potentiation of Excitotoxicity in HIV-1 Associated Dementia and the Significance of Glutaminase
The small intestine also plays a role in the development of hyperammonemia when enterocytes break down glutamine into glutamate and ammonia via glutaminase
enzyme activity (Frederick, 2011).
activity of BNT asparaginase was determined as the two activities were commonly found on the same protein [16,17].