glutamic-oxaloacetic transaminase


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aspartate transaminase

 (AST) (ASAT) [ah-spahr´tāt trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from aspartate to α-ketoglutarate to form glutamate and oxaloacetate, requiring the coenzyme pyridoxal phosphate; it is normally present in serum and in various body tissues, especially in the heart and liver. (See accompanying table.) It is released into the serum as the result of tissue injury, especially injury to the heart or liver, hence the concentration in the serum may be increased in myocardial infarction or acute damage to hepatic cells. Serum levels are also increased in some muscle diseases, such as progressive muscular dystrophy. Called also glutamic-oxaloacetic transaminase.

as·par·tate a·mi·no·trans·fer·ase (AST),

an enzyme catalyzing the reversible transfer of an amine group from l-glutamate to oxaloacetate, forming α-ketoglutarate and l-aspartate; an aid in diagnosing viral hepatitis and myocardial infarction.

as·par·tate a·mi·no·trans·fer·ase

(AST) (as-pahr'tāt ă-mē'nō-trans'fĕr-ās)
An enzyme catalyzing the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming α-ketoglutaric acid and l-aspartic acid; a diagnostic aid in viral hepatitis and in myocardial infarction.
Synonym(s): glutamic-oxaloacetic transaminase, serum glutamic-oxaloacetic transaminase.

glutamic-oxaloacetic transaminase

abbreviated GOT; see aspartate aminotransferase.
References in periodicals archive ?
2], observed that Saudi Arabian crude oil causes decreasing in the specific activities of alkaline phosphatase, [gamma]-glutamyl transpeptidase and leucine aminopeptidase, and increases in the activities of glutamic pyruvic transaminase, glutamic-oxaloacetic transaminase, lactic dehydrogenase and ahydroxybutyric dehydrogenase, that is incompatible with our research results.
Serum levels of proteins, bilirubin and glutamic-oxaloacetic transaminase (GOT) were normal.
Serum cholesterol, glutamic-oxaloacetic transaminase (GOT), and alanin-lactate transaminase (ALT) were measured using a serum autoanalyzer (Roche Co.

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