glucuronide


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glucuronide

 [gloo-ku´ron-īd]
any glycosidic compound of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols, and carboxylic acids.

glu·cu·ro·nide

(glū-kū'rōn-īd),
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (for example, steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Synonym(s): glucuronoside

glucuronide

/glu·cu·ron·ide/ (gloo-ku´ron-īd) any glycosidic compound of glucuronic acid; they are common soluble conjugates formed as a step in the metabolism and excretion of many toxins and drugs, such as phenols and alcohols.

glu·cu·ro·nide

(glū-kyūr'ō-nīd)
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (e.g., steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.

glucuronide

any glycosidic conjugate of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols and carboxylic acids.
References in periodicals archive ?
Incomplete recovery of prescription opioids in urine using enzymatic hydrolysis of glucuronide metabolites.
Bisphenol A glucuronide, a major metabolite in rat bile after liver perfusion.
Moreover, the metabolite hydroxyemodin glucuronide was first reported in this article.
This enabled identification of un-metabolised urinary flavonolignans and urinary phase II metabolites, such as glucuronides, sulphate-glucuronides and diglucuronides.
Paracetamol poisoning (2,4) The majority of paracetamol (90 per cent) is normally metabolised in the liver, via phase II conjugation with glucuronide or sulphate molecules.
Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers.
glucuronide (I-G) and sulfate (I-S) in urine and bile were estimated across various species.
In urine and feces, acyl glucuronide metabolites of febuxostat (~35% of the dose), and oxidative metabolites (~10% of the dose) and a secondary metabolite form, (~14% of the dose) appeared to be the major metabolites of febuxostat in vivo.
Defendants were leading proponents of ethyl glucuronide (EIG) testing.
Urinary tract infection: A risk factor for false-negative urinary ethyl glucuronide but not ethyl sulfate in the detection of recent alcohol consumption.
The NailStat and HairStat EtG tests measure ethyl glucuronide (EtG) - a minor product of alcohol metabolism.
The tester reported that ethyl glucuronide (EtG) had been detected and that the results were consistent with alcohol use in the last month before testing.