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glucuronic acid |
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glucuronic acid /glu·cu·ron·ic ac·id/ (gloo-ku-ron´ik) the uronic acid derived from glucose; it is a constituent of several glycosaminoglycans and also forms conjugates (glucuronides) with drugs and toxins in their biotransformation.
glucuronic acid a uronic acid formed by oxidation of C-6 of glucose to a carboxy group; it occurs in proteoglycans (mucopolysaccharides), and is conjugated in the liver with many natural and foreign compounds or their metabolites, forming glucuronides, which are excreted in the urine. glucuronic acid pathway see glucuronate pathway. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In this study, we found that nonylphenol and octylphenol are also conjugated with glucuronic acid by adult rat liver microsomes. Direct conjugation, in which the steroid is conjugated to glucuronic acid or sulfate, produces a more water-soluble product that can then be excreted in bile and urine (7,10). |
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