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glucosylceramide

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glu·co·syl·cer·a·mide (glk-sl-s-rmd, -sûr-md)
n.
A glycolipid containing a fatty acid, glucose, and sphingosine. Also called glucocerebroside.


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In addition, Enzo Therapeutics is planning the initiation of a Phase II clinical trial to evaluate EGS21, involving an immunomodulatory candidate drug based on glucosylceramide for the management of Crohn's Disease.
A paper on glucosylceramide was presented last May, suggesting that this drug could be an important candidate in the treatment of immune mediated diseases, such as Crohn's, hepatitis B, hepatitis C and HIV.
Since Gaucher Disease is a condition in which glucosylceramide accumulates in the liver, the scientists concluded that its accumulation protects the patient against immune mediated attack on the liver.
 
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