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glucosylceramidase

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glucosylceramidase /glu·co·syl·cer·am·i·dase/ (gloo″ko-sil-ser-am´ĭ-dās) an enzyme that catalyzes the hydrolytic cleavage of glucose from glucocerebrosides to form ceramides in the lysosomal degradation of sphingolipids. Deficiency of enzyme activity, an autosomal recessive trait, results in Gaucher disease.
glucosylceramidase
see β-glucocerebrosidase.


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an analogue of glucosylceramidase, for which it is used as an enzyme replenisher in type 1 Gaucher's disease.
an analogue of glucosylceramidase, for which it is used as an enzyme replenisher in type 1 Gaucher's disease.
 
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