glucosidase


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Related to glucosidase: glucosidase inhibitors

glucosidase

 [gloo-ko´sĭ-dās]
an enzyme of the hydrolase class that splits glucoside, occurring as α-, β-, and α-1,3-glucosidase; α-glucosidase (maltase) occurs in intestinal juice, and β-glucosidase (cellobiase) in the kidney, liver, and intestinal mucosa.

glucosidase

/glu·co·si·dase/ (gloo-ko´sĭ-dās) any of a group of enzymes of the hydrolase class that hydrolyze glucose residues from glucosides; they are specific for α- or β- configurations as well as for particular substrate configurations, e.g., maltase.

glucosidase

(glo͞o-kō′sĭ-dās′, -dāz′)
n.
Any of various enzymes that catalyze glucoside hydrolysis.

glucosidase

an ENZYME catalysing the removal of single GLUCOSE residues from DISACCHARIDES and OLIGOSACCHARIDES.

glucosidase

an enzyme of the hydrolase class that cleaves the glucosidic bond between two glucose molecules, occurring as α-, β- and α-1,3-glucosidase; α-glucosidase (maltase) occurs in intestinal juice, and β-glucosidase (cellobiase) in the kidney, liver and intestinal mucosa.
References in periodicals archive ?
However pioglitazone combination therapy with metformin and alpha glucosidase inhibitors (regimen C and D) revealed lower weight and BMI gain: 0.
Fortunately, a low-cost drug called acarbose effectively inhibits glucosidase.
Glucosidase inhibitors such as deoxynojirimycin (DNM) are reported to be potent antivirals and have been used in the treatment of an HIV infected lymphocyte culture, in which they inhibited the spread of the virus (Papandreou et al.
3 118 399 bacterial glucosidase, 37[degrees]C) mAbs/min (a) Relative sensitivity (b) Proposed method (EPS-G7, 17.
It is one form of a lysosomal storage disorder in the gene producing alpha glucosidase and affects one in 100,000 infants.
PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase II clinical development for the treatment of PKU, BMN 701, a novel fusion protein of insulin-like growth factor 2 and acid alpha glucosidase (IGF2-GAA), which is currently in Phase I/II clinical development for the treatment of Pompe disease, and BMN 673, a poly ADP-ribose polymerase (PARP) inhibitor, which is currently in Phase I/II clinical development for the treatment of genetically-defined cancers.
glucosidase and hesperidinase enzymes were screened in broth under shaking condition among these six cultures.
Five separate enzyme reactions were performed (a glucosidase, [beta]-glucosidase, [alpha]-galactosidase, [beta]-galactosidase, and acid sphingomyelinase) with 5 separate 2-mm dried blood spots and a cassette of synthetic substrates and internal standards.
Celgosivir is an orally administered, first-in-class alpha glucosidase 1 inhibitor, in development for the treatment of chronic hepatitis C virus (HCV) infections.
Infigen met and exceeded the milestones called for under our agreement, including the cloning of numerous dairy cattle for commercial-scale production of bio-active human collagen type I, human fibrinogen, alpha glucosidase and pure gelatin," said Walter Simson, CEO of Infigen.
By inhibiting an enzyme called glucosidase, the drugs apparently reduce the cell-to-cell spread of the AIDS virus (HIV), as well as inhibit the formation of "giant' cells made when uninfected blood cells attach to an HIV-infected cell.