glucose-6-phosphate dehydrogenase


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Related to glucose-6-phosphate dehydrogenase: pentose phosphate pathway, glucose-6-phosphate dehydrogenase test

dehydrogenase

 [de-hi´dro-jen-ās″]
an enzyme that mobilizes the hydrogen of a substrate so that it can pass to a hydrogen acceptor.
glucose-6-phosphate dehydrogenase an enzyme necessary for the oxidation of glucose-6-phosphate, an intermediate in carbohydrate metabolism. Hereditary deficiency of this enzyme in the erythrocytes is associated with a tendency toward hemolysis upon ingestion of certain antimalarial agents and sulfonamide drugs and fava beans (see favism.
lactate dehydrogenase (LDH) an enzyme that catalyzes the interconversion of lactate and pyruvate. It is widespread in tissues and is particularly abundant in kidney, skeletal muscle, liver, and myocardium. It appears in elevated concentrations when these tissues are injured.

glu·cose-6-phos·phate de·hy·dro·gen·ase

(glū'kōs fos'fāt dē'hī-droj'en-ās),
An NADP+-dependent enzyme catalyzing the dehydrogenation of d-glucose 6-phosphate to 6-phospho-d-glucono-δ-lactone, this reaction initiating the pentose shunt. A deficiency of this enzyme can lead to severe hemolytic anemia and favism. A deficiency of the leukocyte enzyme prevents respiratory burst in neutrophils.

glucose-6-phosphate dehydrogenase

/glu·cose-6-phos·phate de·hy·dro·gen·ase/ (G6PD) (-fos´fāt de-hi´dro-jen-ās) an enzyme of the pentose phosphate pathway which, with NADP+ as coenzyme, catalyzes the oxidation of glucose 6-phosphate to a lactone. Deficiency of the enzyme causes severe hemolytic anemia.

glucose-6-phosphate dehydrogenase (G-6-PD)

an important enzyme in the PENTOSE PHOSPHATE PATHWAY for carbohydrate metabolism, catalysing the oxidation of glucose 6-phosphate in the presence of NADP coenzyme, giving 6-phosphogluconolactone and NADPH. G-6-PD of blood erythrocytes is of particular interest because a decrease in its activity can lead to the condition called FAVISM.

dehydrogenase

an enzyme that mobilizes the hydrogen of a substrate so that it can pass to a hydrogen acceptor, such as NAD+ or FAD+.

alcohol dehydrogenase
dimeric enzyme protein of the liver catalyzing the NAD+-linked dehydrogenation of ethanol to acetaldehyde.
glucose-6-phosphate dehydrogenase
see glucose-6-phosphate dehydrogenase.
glutamate dehydrogenase (GD), glutamic dehydrogenase
an enzyme that catalyzes the reversible reaction of glutamic acid into 2-oxoglutaric acid and ammonia. High concentrations occur in the liver of sheep, cattle, horses and dogs. Serum levels are useful in detecting hepatocellular damage in ruminants.
l-iditol dehydrogenase (ID)
a liver specific enzyme; serum determinations have been used in the horse to detect hepatocellular damage. Called also sorbitol dehydrogenase, SDH.
isocitrate dehydrogenase (ICD)
an enzyme found in high concentrations in many tissues. Two major forms of the enzyme, an NAD+-dependent ICD associated with the mitochondrial TCA cycle and a NADP+-dependent ICD associated with fat synthesis in adipose tissue and lactating mammary gland of ruminants or with steroidogenesis in endocrine tissues. Serum levels have been used to detect hepatocellular damage, but it is not highly specific.
lactate dehydrogenase (LDH), lactic acid dehydrogenase
an enzyme that catalyzes the interconversion of lactate and pyruvate. It is widespread in tissues and is particularly abundant in kidney, skeletal muscle, liver and myocardium. It appears in elevated concentrations when these tissues are injured. See also mouse lactic dehydrogenase elevating virus.
lactate dehydrogenase agent
polyol dehydrogenase
sorbitol dehydrogenase (SDH)
References in periodicals archive ?
Role of glucose-6-phosphate dehydrogenase in freezing-induced freezing resistance of Populus suaveolens.
Increasing incidence of hyperbilirubinemia in "unchallenged" glucose-6-phosphate dehydrogenase deficiency in term Saudi newborns.
Development of a novel mouse model of severe glucose-6-phosphate dehydrogenase (G6PD)-deficiency for in vitro and in vivo assessment of hemolytic toxicity to red blood cells," Blood Cells, Molecules, and Diseases, vol.
Glucose-6-phosphate dehydrogenase deficiency: a potential source of severe neonatal hyperbili-rubinaemia and kemicterus.
Glucose-6-phosphate dehydrogenase activity also showed a pattern of up and down with an increase of dietary CBH (Table 4).
Glucose-6-phosphate dehydrogenase deficiency and related disorders of hexose monophosphate shunt and glutathione metabolism.
Glucose-6-phosphate dehydrogenase was assayed by the method of Ellis and Kirkman (1961).
Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency on the other hand is the most common enzymopathy of humans (5).
Galactosaemia, in fact, often results in hypoglycaemia caused by hepatic accumulation of galactose-1phosphate, which inhibits enzymes of glycogenolysis; including glucose-6-phosphatase, glucose-6-phosphate dehydrogenase, phosphoglucomutase and glycogen phosphorylase.
We examined superoxide dismutase (SOD), catalase, glutathione peroxidase, glutathione reductase, and glucose-6-phosphate dehydrogenase (G6PDH) activities, GSH/GSSG ratio and total thiol and carbonyl content.

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