in -cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection.
Rossetti L, Giaccari A, DeFronzo RA: Glucose toxicity
EFFECT OF GLYCATION REVERSAL AGENTS ON GLUCOSE TOXICITY
IN A HALOPHILIC BACTERIUM ISOLATED FROM AN INLAND SALT SPRING.
Specifically, we assessed: (1) deoxyglucose uptake in differentiated C2C12 muscle cells and 3T3-L1 adipocytes; (2) glucose-stimulated insulin secretion (GSIS) in [beta] TC-tet pancreatic [beta] cells; (3) [beta] cell proliferation in [beta] TC-tet cells; (4) lipid accumulation in differentiating 3T3-L1 cells; (5) protection against glucose toxicity
in PC12 cells.
Not only does it bring down blood glucose, it may act synergistically with other agents to reduce glucose toxicity