glucose clearance

glucose clearance

A value corresponding to the rate of glucose uptake divided by plasma glucose concentration
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Blocking the growth factor early in development in a mouse model ultimately reduced beta-cell mass and insulin release and impaired glucose clearance from the bloodstream.
7), (14-16) Since muscle is responsible for 70% to 90% of glucose clearance and determines 40% of a person's insulin sensitivity, it makes sense to attack insulin resistance through movement.
A study at the University of Chicago showed that limiting sleep to 4 hours per night for 6 nights in healthy young adults produced evidence of impaired glucose clearance and increased insulin resistance, Dr.
The Bergman concept, which distinguishes insulin-dependent and insulin-independent components of glucose clearance (indicated by insulin sensitivity and glucose effectiveness, respectively), may resolve these apparently discrepant results (24).
This latest study also indicated that, aside from fat combustion, UCP3 at high levels also produced other effects of interest for drug discovery: The transgenic mice exhibited 70% lower cholesterol levels than those of the controls, lower fasting glucose levels and lower insulin levels, and increased glucose clearance rates.
Beysen reported that the improved glycemic control with Welchol was accompanied by an effect on incretins, improvement in glucose clearance and whole-body glycolytic disposal of glucose.
Brooks noted that a woman's metabolism changes as her hormone levels change after menopause, affecting glucose clearance from the blood, for example.
This is why the muscle mass of an individual determines 40% of his or her insulin sensitivity and 70% to 90% of blood glucose clearance.
In the male diabetic fa/fa Zucker rat model as well as in the poly-genetic Diet-Induced-Obese (DIO) rat model, sub-chronic administration of PSN9301 increased blood glucose clearance to a similar degree to Metformin, and its combination with Metformin further improved glucose homeostasis compared to Metformin and PSN9301 alone.