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glucocerebroside

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
glucocerebroside /glu·co·cer·e·bro·side/ (-ser´ĕ-bro-sīd″) a cerebroside with a glucose sugar.
glu·co·cer·e·bro·side (glk-sr-br-sd, -s-r-)

Glucocerebroside
A cerebroside that contains glucose in the molecule.
Mentioned in: Gaucher Disease

glucocerebroside [gloo″ko-ser´ĕ-bro-sīd]
a cerebroside containing a glucose sugar; it accumulates in the tissues in Gaucher's disease.

glucocerebroside
a cerebroside containing a glucose sugar; it accumulates in the tissues in gaucher's disease (glucocerebrosidosis).


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Gaucher''s disease is a rare, inherited disorder that causes too much of a substance called glucocerebroside to build up in your spleen, liver, lungs, bones and sometimes in your brain.
Deficient GCase activity leads to lysosomal accumulation of glucocerebroside inside certain cells, which is believed to cause the various symptoms of Gaucher disease, including an enlarged liver and spleen, abnormally low levels of red blood cells and platelets and skeletal complications.
Prevalence of glucocerebroside mutations in the Israeli Ashkenazi Jewish population.
 
 
 
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