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glucagonoma syndrome |
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glucagonoma syndrome [glo̅o̅′kəgonō′mə] Etymology: Gk, glykys + agaein + oma, tumor a disease associated with a glucagon-secreting tumor of the islet cells of the pancreas. It is characterized by hyperglycemia, stomatitis, glossitis, anemia, weight loss, and a characteristic rash. Treatment is surgical removal of the tumor. glucagonoma syndrome A symptom complex associated with glucagonoma, a tumor of post-menopausal ♀ who often have DM, blistering dermatitis–necrolytic migratory erythema, epidermal necrosis, subcorneal pustules, suppurative
folliculitis, confluent parakeratosis, epidermal hyperplasia, and prominent papillary dermal hyperplasia, weight loss, normochromic anemia, ileus, constipation or diarrhea, glossitis, angular cheilitis, venous thrombosis, hypoproteinemia,
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The glucagonoma syndrome includes increased hepatic gluconeogenesis and hyperglycemia, muscle catabolism with associated wasting, and an unusual cutaneous eruption known as necrolytic migratory erythema, sometimes with associated stomatitis or cheilosis. |
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