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glucagon-like peptide 1

   Also found in: Acronyms, Wikipedia 0.01 sec.
glucagon-like peptide 1 (GLP-1),
an appetite suppressing substance found in the brain and intestine. In the brain, GLP-1 acts as a satiety signal. In the intestine it slows emptying of the stomach and stimulates the release of insulin from the pancreas.


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Abstract: Exenatide (synthetic exendin-4) is the analog of glucagon-like peptide 1 (GLP-1), the major physiologic incretin.
Called glucagon-like peptide 1 (GLP1), the beneficial compound stimulates the release of insulin from the pancreas and maintains insulin-making beta cells housed in that organ.
The efficacy of DPP-IV inhibitors is mediated primarily via stabilization of the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).
 
 
 
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