glomus tumor


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Related to glomus tumor: glomus jugulare tumor, glomus jugulare

tumor

 [too´mor]
1. swelling or morbid enlargement; this is one of the cardinal signs of inflammation.
2. a new growth of tissue in which cell multiplication is uncontrolled and progressive. Tumors are also called neoplasms, which means that they are composed of new and actively growing tissue. Their growth is faster than that of normal tissue, continuing after cessation of the stimuli that evoked the growth, and serving no useful physiologic purpose. adj., adj tu´morous.

Tumors are classified in a number of ways, one of the simplest being according to their origin and whether they are malignant or benign. Tumors of mesenchymal origin include fibroelastic tumors and those of bone, fat, blood vessels, and lymphoid tissue; they may be benign or malignant (sarcoma). Tumors of epithelial origin are found in glandular tissue and such organs as the breast, stomach, uterus, or skin; they also may be either benign or malignant (carcinoma). Mixed tumors contain different types of cells derived from the same primary germ layer, and teratomas contain cells derived from more than one germ layer; both kinds may be benign or malignant.
Benign Tumors. Benign tumors do not endanger life unless they interfere with normal functions of other organs or affect a vital organ. They grow slowly, pushing aside normal tissue but not invading it. They are usually encapsulated, well demarcated growths. They are not metastatic; that is, they do not form secondary tumors in other organs. Benign tumors usually respond favorably to surgical treatment and some forms of radiation therapy.
Malignant Tumors. These tumors are composed of embryonic, primitive, or poorly differentiated cells. They grow in a disorganized manner and so rapidly that nutrition of the cells becomes a problem. For this reason necrosis and ulceration are characteristic of malignant tumors. They also invade surrounding tissues and are metastatic, initiating the growth of similar tumors in distant organs. (See also cancer.)
Gross appearance of benign (A) and malignant (B) tumors. From Damjanov, 2000.
benign tumor one that lacks the properties of invasiveness and metastasis and that is usually surrounded by a fibrous capsule; its cells also show a lesser degree of anaplasia than those of a malignant tumor do.
bladder tumor a tumor of the urinary bladder; see also bladder cancer.
brain tumor see brain tumor.
brown tumor a giant-cell granuloma produced in and replacing bone, occurring in osteitis fibrosa cystica and due to hyperparathyroidism.
Burkitt's tumor Burkitt's lymphoma.
Buschke-Löwenstein tumor a slow-growing mass of warts found usually in the prepuce but sometimes elsewhere in the perianal region; it starts as a plaque and may grow into a large cauliflowerlike mass. Called also giant condyloma.
carcinoid tumor carcinoid (def. 1).
carotid body tumor a chemodectoma of a carotid body, found as a firm round mass at the bifurcation of the common carotid artery.
connective tissue tumor any tumor arising from a connective tissue structure, such as a fibroma or sarcoma.
desmoid tumor desmoid (def. 1).
endodermal sinus tumor yolk sac tumor.
erectile tumor cavernous hemangioma.
Ewing's tumor Ewing's sarcoma.
false tumor pseudotumor.
fibroid tumor
germ cell tumor any of a group of tumors arising from primitive germ cells, usually of the testis or ovum; they range from benign to highly malignant. Types include germinoma, yolk sac tumor, teratoma, embryonal carcinoma, and some types of choriocarcinoma; many tumors are mixtures of types.
giant cell tumor
1. a benign or malignant tumor containing giant cells; see under carcinoma, granuloma, and sarcoma.
2. a bone tumor, ranging from benign to frankly malignant, composed of cellular spindle cell stroma containing multinucleated giant cells resembling osteoclasts.
3. a small yellow benign tumorlike nodule of tendon sheath origin, usually of the wrist and fingers or ankle and toes, laden with lipophages and containing multinucleated giant cells.
glomus tumor
1. a blue-red, extremely painful chemodectoma involving an arteriovenous anastomosis or cluster of blood cells, which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. Such tumors may also occur in the stomach and nasal cavity.
granular cell tumor a relatively common neoplasm whose cells have a granular appearance by light microscopy; it is usually benign but occasionally malignant, and multiple tumors may occur. It can be found anywhere but is most often seen in the oral cavity, especially in the tongue.
granulosa tumor (granulosa cell tumor) see granulosa cell tumor.
granulosa-theca cell tumor see granulosa-theca cell tumor.
heterologous tumor one made up of tissue differing from that in which it grows.
homoiotypic tumor (homologous tumor) one made up of tissue resembling that in which it grows.
Hürthle cell tumor see hürthle cell tumor.
islet cell tumor a tumor of the islands of Langerhans; many secrete excessive amounts of hormones. Types include gastrinoma, glucagonoma, insulinoma, somatostatinoma, and vipoma.
Krukenberg's tumor see krukenberg's tumor.
lipoid cell tumor of ovary a usually benign ovarian tumor composed of eosinophilic cells or cells with lipoid vacuoles; it causes masculinization.
tumor lysis syndrome severe hyperphosphatemia, hyperkalemia, hyperuricemia, and hypocalcemia occurring after effective induction chemotherapy of rapidly growing malignant neoplasms; thought to be due to release of intracellular products after cell lysis.
malignant tumor one that has the properties of invasiveness and metastasis and that shows a greater degree of anaplasia than a benign tumor does.
mast cell tumor mastocytoma.
melanotic neuroectodermal tumor a benign, rapidly growing, dark tumor of the jaw or occasionally some other site, almost always seen in infants; called also melanoameloblastoma.
mixed tumor one composed of more than one type of neoplastic tissue.
tumor necrosis factor receptor–associated periodic syndrome (TRAPS) familial periodic fever.
organoid tumor teratoma.
peripheral neuroectodermal tumor (PNET) any of a heterogeneous group of neoplasms originating in supporting structures or neuronal tissue, primarily of the extremities, pelvis, or chest wall; seen most often in adolescents and young adults and frequently having widespread metastases.
plasma cell tumor
1. plasma cell dyscrasias.
sand tumor psammoma.
Sertoli-Leydig cell tumor androblastoma (def. 1).
theca cell tumor a fibroidlike tumor of the ovary containing yellow areas of fatty material derived from theca cells.
turban t's multiple cylindromas of the scalp that are grouped together so as to cover the entire scalp.
Wilms' tumor a rapidly developing malignant mixed tumor of the kidneys, made up of embryonal elements, occurring chiefly in children before the seventh year; a genetic component is suspected in its etiology. It may be accompanied by congenital defects such as urinary tract abnormalities, absent iris of the eye, and asymmetry of parts. With treatment, the prognosis is excellent. Called also embryonal carcinosarcoma and nephroblastoma.
yolk sac tumor a malignant germ cell tumor of children that represents a proliferation of both yolk sac endoderm and extraembryonic mesenchyme. It produces α-fetoprotein and most often occurs in the testes, but is also seen in the ovaries and some extragonadal sites. Called also endodermal sinus tumor.

glo·mus tu·mor

[MIM*138000]
a vascular neoplasm composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses that may be several millimeters in diameter and occur almost exclusively in the skin, often subungually in the upper extremity; it is exquisitely tender and may be so painful that patients voluntarily immobilize an extremity, sometimes leading to atrophy of muscles; multiple glomus tumors occur, sometimes with autosomal dominant inheritance. Tumors with cavernous spaces lined by glomus cells are called glomangiomas.

glomus tumor

a frequently painful neoplasm involving the arteriovenous anastomoses of the skin. It contains many small vascular channels surrounded by glomus cells.
enlarge picture
Glomus tumors

glomus tumor

Glomangioma A neoplasm that is most common in age 20-40 which arises in the neuromyoarterial glomus, an AV shunt Clinical When located in the 'usual' subungual site, the abundant innervation makes the tumor exquisitely painful; when located elsewhere–eg, middle ear, stomach, it is painless. Cf Hemagiopericytoma.

glo·mus tu·mor

(glō'mŭs tū'mŏr)
An unusual vascular neoplasm composed of specialized pericytes, usually in nodular masses, which occurs almost exclusively in the skin; it is exquisitely tender and may be so painful that patients voluntarily immobilize an extremity.
See also: glomangioma

glomus

pl. glomera [L.] a small histologically recognizable body composed primarily of fine arterioles connecting directly with veins, and having a rich nerve supply.

glomus caroticum
carotid body.
glomus cell
a specialized cell of the carotid body.
glomus choroideum
an enlargement of the choroid plexus of the lateral ventricle.
glomus tumor
neoplasm of one of the chemoreceptors. Tumors of the glomus jugulare have been reported in a dog.
References in periodicals archive ?
Glomus tumor of the stomach simulating a gastrointestinal stromal tumor: a case report and review of literature.
Glomangiopericytoma is a solid glomus tumor with hemangiopericytoma-like foci and is differentiated from myopericytoma by a lack of the characteristic perivacular onion-skin pattern.
Intravascular tumor has also been described by Michal[3] in a case of solitary glomus tumor proper of the foot.
18,30-34] The histology ranges from a typical glomus tumor composed of compact epithelioid cells to tumors indistinguishable from perivascular myoma.
2, and epithelial membrane antigen), compatible with the diagnosis of glomus tumor.
A preliminary diagnosis of glomus tumor was made; the differential diagnosis included ELST and hemangiopericytoma.
The glomus tumor was treated with embolization followed by radiotherapy; the schwannoma was left alone under radiologic observation.
The surgical management of these disorders includes cochlear implants, stapes surgery, tympanomastoidectomy procedures, and removal of small glomus tumors.
These tumors represent less than 1% of all soft tissue tumors; until now, only two cases of a glomus tumor involving the auricle have been reported.
There are several classification systems for glomus tumors, such as the modified Jackson classification table (Greenberg, 2001), which grade the lesion based upon extension into the internal auditory canal or petrous apex.
Neurologic manifestations of glomus tumors in the head and neck.
Neurovascular considerations in surgery of glomus tumors with intracranial extensions.