glomerular filtration

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Related to glomerular filtration: tubular reabsorption

glomerular filtration

the renal process whereby fluid in the blood is filtered across the capillaries of the glomerulus and into the urinary space of Bowman's capsule.


passage through a filter or through a material that prevents passage of certain molecules, e.g. capillary wall, blood-brain barrier, radiographic grid.

filtration angle
developmental or acquired distortion of this part of the eye is the common cause of glaucoma. It is the space bounded by the sclera externally, the ciliary muscle posteriorly, the root of the iris medially and the anterior chamber of the eye anteriorly. Within the space is the filtering mechanism, a mass of anastomosing mesodermal spindle cells with many perforations between them.
filtration barrier
the physiological function which limits the passage of small molecules through the renal corpuscle.
glomerular filtration
the process by which glomerular filtrate is formed, involving the balance of pressures across the walls of the glomerular capillaries.
inherent filtration
attenuation of the primary x-ray beam as a result of its passage out of the x-ray tube through the insulating medium and tube window.
filtration membrane
the membrane which stretches across the filtration slits in the renal corpuscle.
filtration pressure
the net driving force which pushes fluid into tissue spaces and out of vascular sites; the net result between capillary osmotic pressure and intravascular hydrostatic pressure.
filtration slits
openings in the glomerular corpuscle which are part of the filtration process in the renal glomerulus.


pertaining to or of the nature of a glomerulus, especially a renal glomerulus.

glomerular basement membrane
the structure located between endothelial cells of renal capillaries and the visceral epithelial cells of the glomerulus. It functions as a barrier to filtration of large molecules.
glomerular capsule
Bowman's capsule.
glomerular crescent
see glomerular crescent.
glomerular filtrate
the acellular low-protein ultrafiltrate of plasma that passes the glomerulus.
glomerular filtration
glomerular filtration rate
varies widely depending on diet. It is the ability of the renal tubules to vary their absorbing capacity that ensures there is no great electrolyte loss during the periods of high rates of glomerular filtration.
glomerular lipidosis
characterized by the presence of large foam cells in glomerular tufts in dogs. They appear to have no disease significance.
glomerular permeability
in normal subjects the capillary endothelium of the glomerulus, by virtue of its fenestration, is permeable to all blood constituents except blood cells and colloids so that the glomerular filtrate has a close similarity to plasma and interstitial fluid but has a lower protein concentration than both of them.
References in periodicals archive ?
In spite of the insufficient literature discussion about it, a reduced glomerular filtration rate may be an important pathophysiological mechanism (3, 4).
At the May 2005 National Kidney Foundation Annual Meeting, the abstract Short Term Treatment With Rosuvastatin Increases Estimated Glomerular Filtration Rate looked at the effect of CRESTOR on estimated glomerular filtration rate (eGFR) by analyzing 13 clinical trials including 3,956 patients.
Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease.
population having reduced glomerular filtration rate and/or proteinuria, a condition in which a person has an abnormal amount of protein in the blood and a sign often associated with kidney disease.
PHILADELPHIA - Early, intensive treatment for type 1 diabetes with conventional therapy halves the long-term risk of developing an impaired glomerular filtration rate, the common pathway leading to end-stage kidney disease, Dr.
The University of Miami researchers now report that patients with earlier stage kidney disease and high FGF23 are at nearly two times higher risk of kidney failure if their baseline estimated glomerular filtration rate (eGFR) is 45 milliliters or higher, while all CKD patients are at three times higher risk of death compared to patients with lower levels of the hormone.
Glomerular filtration rate (eGFR) is a test that describes the flow rate of fluid going through the kidneys and is associated with early dialysis initiation.
A meta-analysis conducted by the Chronic Kidney Disease Prognosis Consortium concluded that elevations in urinary albumin and blood albumin to creatinine ratio, which indicate kidney damage, as well as a reduction in the estimated glomerular filtration rate of the kidneys predict an increased risk of death from all causes over 2.
Adoption of the calculated glomerular filtration rate (also known as electronic glomerular filtration rate, or eGFR) as an adjunct to or replacement for the 24-hour urine creatinine clearance test has not been without its problems.
Internationally, clinical guidelines recommend the use of creatinine-based equations to estimate glomerular filtration rate (GFR) for assessment and follow-up of kidney disease.
Increased cadmium was also associated with decreased creatinine clearance, reflecting a reduced glomerular filtration rate.