glomerular cyst

glo·mer·u·lar cyst

cyst formed by dilation of Bowman capsule, found in rare cases of congenital polycystic kidneys.

glo·mer·u·lar cyst

(glō-mer'yū-lăr sist)
Cyst formed by dilation of Bowman capsule, found in rare cases of congenital polycystic kidneys.
References in periodicals archive ?
15-17) In the past, a more liberal application of the term glomerulocystic kidney was used even in the presence of the "occasional" glomerular cyst.
Ischemic damage is thought to cause outflow obstruction resulting in glomerular cyst formation.
Increased pressure in the Bowman space as the cause of glomerular cyst formation is indirectly supported by electron microscopy.
94,98,215-217) However, in combination with the abnormal presence of uromodullin within glomerular cysts, (218,219) a possible mechanism for glomerular cyst formation has been proposed as follows: tubular obstruction and subsequent reflux of prourine, containing uromodullin, into the Bowman space causes glomerular cysts.
Earlier reports have depicted glomerular cysts and have portrayed similar cases of "congenital cystic kidney with glomerular cysts" (2,3,4) (Figure 1, A and B).
7) In this study we propose a diagnostic classification in 5 categories of the entities presenting with glomerular cysts (Table 1): type I, PKD presenting as a GCK variant of autosomal recessive polycystic kidney disease (ARPKD)/ADPKD (with or without liver disease); type II, hereditary GCK synonymous with GCKD.
A summary of the pathogenesis of glomerular cysts is complemented by an in silico analysis of existing data sets, which delineates common molecular and genetic relationships between ostensibly distinct clinical entities.
20,45,46,49,54,55) A possible explanation for the different clinical presentations and variability in rate of progression is that glomerular cysts may affect only a minority of the glomeruli, but the fact remains that most cases progress to end-stage renal disease.
In adults the radiologic diagnosis of GCK is less problematic, but glomerular cysts are frequently missed because their detection is below the threshold of ultrasonography or computed tomography.
Histologically, glomerular cysts were present (Figure 3, A) but cysts were also seen in the medulla; these cysts were focally fusiform and suggested a tubular origin (Figure 3, B).
Dr Liapis addresses differential diagnosis and clinical relevance by using beautiful examples of GCK from her personal files and proposes a classification of GCK, based upon genetic defects and clinicopathologic features, that offers a level of conceptual clarity previously lacking in the diverse diseases associated with glomerular cysts.
28) In some cases glomerular cysts due to dilatation of the urinary space are widespread and contribute to the cystic appearance of the kidney.