Isolation and localization of the antibiotics gliotoxin
produced by Gliocladium virens from alginate prill in soil and soilless media.
fumigatus toxins, including gliotoxin
, helvolic acid and fumagillin (Takashi et al.
In addition, Trichoderma virens produced gliotoxin
toxic to both R.
Induction of mutagenesis by gamma irradiation can also increase the ability of Trichoderma species to produce antibiotics and phenolic compounds such as trichodermine, gliotoxin
and viridian (Haggag and Mohamed, 2002).
NF-[kappa]B inhibitors, including pyrrolidine dithiocarbamate , parthenolide , gliotoxin
, and proteosome inhibitor , were reported to cause GSH depletion.
production by clinical and environmental Aspergillusfumigatusstrains.
Mycotoxins produced by candida include gliotoxin
, which is known to suppress the immune system.
contamination in and pre- and postfermented corn, sorghum and wet brewer's grains silage in Sao Paulo and Rio de Janeiro State, Brazil.
Cellular targeting of the apoptosis-inducing compound gliotoxin
to fibrotic rat livers.
Di Pietro A, Lorito M, Hayes CK, Broadway RM, Harman GE (1993) Endochitinase from Gliocladium virens: Isolation, characterization and synergistic antifungal activity in combination with gliotoxin
The effective antifungal compounds produced by this fungus were identified as gliovirin and gliotoxin
, but no further purification and dose response of these compounds were done in the study.