Isolation and localization of the antibiotics
gliotoxin produced by Gliocladium virens from alginate prill in soil and soilless media.
fumigatus toxins, including
gliotoxin, helvolic acid and fumagillin (Takashi et al.
In addition, Trichoderma virens produced
gliotoxin toxic to both R.
Induction of mutagenesis by gamma irradiation can also increase the ability of Trichoderma species to produce antibiotics and phenolic compounds such as trichodermine,
gliotoxin and viridian (Haggag and Mohamed, 2002).
NF-[kappa]B inhibitors, including pyrrolidine dithiocarbamate [36], parthenolide [37],
gliotoxin [38], and proteosome inhibitor [24], were reported to cause GSH depletion.
Gliotoxin production by clinical and environmental Aspergillusfumigatusstrains.
Mycotoxins produced by candida include
gliotoxin, which is known to suppress the immune system.
Gliotoxin contamination in and pre- and postfermented corn, sorghum and wet brewer's grains silage in Sao Paulo and Rio de Janeiro State, Brazil.
Cellular targeting of the apoptosis-inducing compound
gliotoxin to fibrotic rat livers.
Di Pietro A, Lorito M, Hayes CK, Broadway RM, Harman GE (1993) Endochitinase from Gliocladium virens: Isolation, characterization and synergistic antifungal activity in combination with
gliotoxin.
The effective antifungal compounds produced by this fungus were identified as gliovirin and
gliotoxin, but no further purification and dose response of these compounds were done in the study.