gliosarcoma


Also found in: Dictionary, Wikipedia.
Related to gliosarcoma: glioblastoma, glioma

gliosarcoma

 [gli″o-sahr-ko´mah]
glioma combined with sarcoma.

gli·o·sar·co·ma

(glī'ō-sar-kō'mă),
A glioblastoma multiforme with an associated malignant mesenchymal component. Sometimes used as a term for a malignant neoplasm derived from connective tissue (for example, that associated with blood vessels in the brain) in which there are proliferating glial cells.

gliosarcoma

[glī′ōsärkō′mə] pl. gliosarcomas, gliosarcomata
Etymology: Gk, glia + sarx, flesh, oma, tumor
a tumor composed of spindle-shaped cells in the delicate supporting connective tissue of nerve cells. Also called glioblastoma, glioma, spongioblastoma, spongiocytoma.

gliosarcoma

Neuropathology A glioblastoma with sarcomatous elements Prognosis Poor, highly aggressive; most Pts die within 1 yr

gli·o·sar·co·ma

(glī'ō-sahr-kō'mă)
A glioblastoma multiforme with an associated malignant mesenchymal component. Sometimes used as a term for a malignant neoplasm derived from connective tissue (e.g., that associated with blood vessels in the brain) in which there are proliferating glial cells.
[G. glio, glue + sarco, flesh + -oma, tumor]
References in periodicals archive ?
Additionally, the report provides an overview of key players involved in therapeutic development for Gliosarcoma and features dormant and discontinued projects.
Clinical outcome of gliosarcoma compared with glioblastoma multiforme: North Central Cancer Treatment Group results," Journal of Neurosurgery, vol.
The report reviews key players involved in the therapeutics development for Gliosarcoma and enlists all their major and minor projects
En la literatura existen varios reportes de casos de Gliosarcoma cerebral, pero solo muy pocos casos de GS de cerebelo estan reportados (5,6,7,8).
Gliosarcoma is a glioblastoma variant with different areas displaying glial and mesenchymal differentiation.
25,26) Additionally, molecular studies have confirmed the concept of giant cell glioblastoma and gliosarcoma as distinct variants.
Ensayos con nanoesferas de hexadecil-cianoacrilato muestran la capacidad selectiva de unirse a celulas de gliosarcoma en modelos de rata y se ha utilizado doxorrubicina unida a nanoparticulas en modelos de glioblastoma multiforme en roedores, en los que se ha obtenido una remision significativa con minima toxicidad.
Son llamativas las posibles aplicaciones del SFV en terapia contra el cancer, pues se ha visto que puede inducir apoptosis en lineas de glioma y gliosarcoma de rata (30) y en lineas de tumores de prostata humana (31).
A snapshot of the global therapeutic scenario for Gliosarcoma.
Simon Cancer Center is one of four sites in the country to begin a Phase III clinical trial of the novel drug VAL-083 for patients whose glioblastoma multiforme or gliosarcoma has progressed during or after treatment with the standard of care chemo-radiation therapy.
Only 3 distinct morphologic variants of GBM are currently recognized by the current World Health Organization classification scheme, including GBM, giant cell GBM, and gliosarcoma.
Global Markets Direct's, 'Gliosarcoma - Pipeline Review, H1 2012', provides an overview of the Gliosarcoma therapeutic pipeline.