GLI4

(redirected from glioma-associated oncogene family zinc finger 4)

GLI4

A gene on chromosome 8q24.3 that encodes a DNA-binding C2H2-type zinc finger protein of the Gli family, which plays a role in limb development. The full-length GLI3 (GLI3FL) is a transcriptional activator; GLI3R, the C-terminally truncated form, acts as a repressor of the sonic hedgehog (Shh) pathway.