glioblastoma

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Related to glioblastomas: meningiomas, gliomas

glioblastoma

 [gli″o-blas-to´mah]
any malignant astrocytoma.
glioblastoma multifor´me astrocytoma grade III or IV; a rapidly growing tumor, usually of the cerebral hemispheres, composed of spongioblasts, astroblasts, and astrocytes.

glioblastoma

/glio·blas·to·ma/ (gli″o-blas-to´mah) any malignant astrocytoma.
glioblastoma multifor´me  the most malignant type of astrocytoma, composed of spongioblasts, astroblasts, and astrocytes; it usually occurs in the brain but may occur in the brain stem or spinal cord.

glioblastoma

(glē′ō-blă-stō′mə, glī′-)
n. pl. glioblasto·mas or glioblasto·mata (-mə-tə)
A malignant tumor of the central nervous system, usually occurring in the cerebrum of adults.

glioblastoma

glioblastoma

Astrocytoma, grade III-IV, glioblastoma multiforme, malignant astrocytoma Neurosurgery A highly aggressive 1º brain tumor–BT arising in glia, comprising 30% of the 5000 new BTs/yr, US At risk occupations Anatomists, pathologists, dentists, ophthalmologists Treatment Poor response to surgery, chemotherapy, RT. See Gliadel® wafer.

glioblastoma

an undifferentiated malignant astrocytoma.

glioblastoma multiforme
a rapidly growing tumor, usually of the cerebral hemispheres, often supratentorial.
References in periodicals archive ?
She said that for individuals with glioblastomas, this finding identified a target for the development of a drug treatment option that currently does not exist.
Beginning with an animal model, the researchers found that they could reduce the growth of medullo-blastomas (the main group of brain tumors to which glioblastomas belong) by 72% using a drug combination including valganciclovir to combat CMV infection.
According to the American Cancer Society, about 30% of brain tumors are gliomas, a fast-growing, treatment-resistant type of tumor that includes glioblastomas, astrocytomas, oligodendrogliomas, and ependymomas.
Verma's team infected a small number of brain cells in mice with viruses carrying genes that reproduce alterations found in patients with glioblastoma.
Glioblastoma, the brain cancer that killed Senator Edward Kennedy, inevitably returns after tumor-removal surgery, chemotherapy, and/or radiation.
Glioblastoma multiforme is the most malignant tumor in the central nervous system and is known for its highly migratory and invasive behavior, according to the team.
Karni can help in assessing the subtype and severity of glioblastoma tumors.
Analyses of PRiDe, a registry of 457 recurrent glioblastoma patients, demonstrate that patients treated with the NovoTTF-100A System at their first and second recurrences had median overall survivals of 20.
That suggested that every cell in these tumours or glioblastomas has the ability to make new glioblastomas," Verma said.
We are excited by the telomerase inhibition observed in the glioblastoma model.
The investigators analyzed several hundred tumor samples collected from glioblastoma patients treated at several institutions between 1989 and 2009, and found NFKBIA deletions in a surprisingly high proportion, 25 percent, of the samples.
Enzastaurin Study Enrolling Patients with Glioblastoma