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glioblastoma

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glioblastoma /glio·blas·to·ma/ (gli″o-blas-to´mah) any malignant astrocytoma.
glioblastoma multifor´me  the most malignant type of astrocytoma, composed of spongioblasts, astroblasts, and astrocytes; it usually occurs in the brain but may occur in the brain stem or spinal cord.

gli·o·blas·to·ma (gl-bl-stm, gl-)
n.
A glioma consisting chiefly of undifferentiated anaplastic cells frequently arranged radially about an irregular focus of necrosis, usually occurring in the cerebrum of adults. Also called grade IV astrocytoma.

glioblastoma.
glioblastoma
an undifferentiated malignant astrocytoma.

glioblastoma multiforme
a rapidly growing tumor, usually of the cerebral hemispheres, often supratentorial.

glioblastoma
Astrocytoma, grade III-IV, glioblastoma multiforme, malignant astrocytoma Neurosurgery A highly aggressive 1º brain tumor–BT arising in glia, comprising 30% of the 5000 new BTs/yr, US At risk occupations Anatomists, pathologists, dentists, ophthalmologists Treatment Poor response to surgery, chemotherapy, RT. See Gliadel® wafer.


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TEMODAL (temozolomide) Capsule is an oral, cytotoxic alkylating agent indicated for treating glioblastoma multiforme (GBM).
Next, the researchers implanted human glioblastoma tumors into mice, some of which had functional genes that encode ING4 protein and others that had defective genes and little ING4 protein.
Glioblastoma is the most common primary brain tumor and one of the most aggressive forms of brain cancer, primarily effecting adults over the age of 50.
 
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