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glial cell

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gli·al cell (gll, gll)
n.
Any of the cells making up the neuroglia, especially the astrocytes, oligodendroglia, and microglia.


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Topics include specialized neurotransmitter transporters in astrocytes, regulation of potassium by glial cells in the central nervous system, calcium ion signaling in astrocytes, the tripartite synapse, molecular approaches for studying astrocytes, mechanisms of transmitter release from astrocytes, and the role of astrocytes in epilepsy.
Mandel's research group has concentrated on using an adeno-associated virus to engineer brain cells in animal models with genes that can protect dopamine-producing cells, which then do the vital work of producing glial cell line-derived neurotrophic factor (GDNF).
In addition, they activate glial cells to produce free radicals (superoxide and NO) and neurotoxic cytokines such as TNF-alpha.
 
 
 
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