KLK2

(redirected from glandular kallikrein 2)

KLK2

A gene on chromosome 19q13.33 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK2 is highly expressed in prostate cancer and may serve as a prognostic marker for prostate cancer.
References in periodicals archive ?
The patent contains composition claims for thapsigargin-containing prodrugs that can be radiolabelled and then activated by the enzymes Prostate Specific Membrane Antigen (PSMA), Prostate Specific Antigen (PSA) or Human Glandular Kallikrein 2 (hK2).
Human glandular kallikrein 2 (hK2) expression in prostatic intraepithelial neoplasia and adenocarcinoma: a novel prostate cancer marker.
This article will discuss the biochemistry of PSA (human glandular kallikrein 3, or hK3) and its molecular forms, and human glandular kallikrein 2 (hK2), another member of the human kallikrein gene family.
Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade.
Prostate specific antigen (PSA) isoforms and human glandular kallikrein 2 (hK2): which offers the best screening performance in a predominantly African American population?
Comparison of human prostate specific glandular kallikrein 2 and prostate specific antigen gene expression in prostate with gene amplification and overexpression of prostate specific glandular kallikrein 2 in tumor tissue.
Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids.
Human glandular kallikrein 2 (hK2) is a serine protease very similar to PSA.
Decreased concentrations of prostate-specific antigen and human glandular kallikrein 2 in malignant versus nonmalignant prostatic tissue.
Human glandular kallikrein 2 (hK2) [6] is a prostatic secretory protein (1) expressing 80% identity in amino acid (2) sequence to prostate-specific antigen (PSA).
Highly sensitive automated chemiluminometric assay for measuring free human glandular kallikrein 2.