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glandular differentiation

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glandular differentiation
The appearance in a carcinoma of glands and gland-like elements which, in an adenoCA, indicates some maturation, which generally is associated with a better prognosis


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Much like the more common MMMTs of ovarian and endometrial origin, MMMTs of the fallopian tube show carcinomatous elements with predominantly glandular differentiation which may assume endometrioid, clear cell, and papillary serous patterns; less commonly, squamous differentiation or undifferentiated carcinomas may be seen.
3 Interestingly, the epithelial cells are positive for S100 protein, even though they show glandular differentiation in every other aspect.
Infiltrating urothelial carcinoma with glandular differentiation is defined by the presence of true glandular spaces within a urothelial carcinoma.
 
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