glanders (redirected from glanderous)

glanders /glan·ders/ (glan´derz) a contagious disease of horses, communicable to humans, due to Pseudomonas mallei, and marked by purulent inflammation of the mucous membranes and cutaneous eruption of nodules that coalesce and break down, forming deep ulcers, which may end in necrosis of cartilage and bone; the more chronic and constitutional form is known as farcy.

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glanders

Etymology: OFr, glandres, neck gland swelling

an infection caused by the bacillus Burkholderia mallei (formerly called Pseudomonas mallei), transmitted to humans from horses and other domestic animals. It is characterized by purulent inflammation of the mucous membranes and development of skin nodules that ulcerate. If untreated with antibiotics, the infection may spread to the bones, liver, central nervous system, and other tissues and cause death. It is endemic in Africa, Asia, and South America but has been eradicated in Europe and North America. Infection has been seen in laboratory workers because of the low infectious dose. It is considered a potential agent for bioterrorism.

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glanders

a contagious disease of all solipeds caused by Burkholderia (Pseudomonas) mallei and transmissible to humans. It occurs in a chronic or acute form, both of which are inexorably fatal. It is characterized by the development of ulcers or nodules on the skin and in the respiratory tract. In the acute form the critical lesion is bronchopneumonia. See also farcy.

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glanders

Infection by Pseudomonas mallei, a gram-negative aerobic bacillus, which affects large domestic animals, most commonly horses, and is rare in the US; human disease occurs in the form of acute, often fatal, septicemia, chronic mucocutaneous disease or pulmonary infection Clinical From cellulitis to necrosis and granulomas with draining ulcers, pleuritis, necrotizing lobar or bronchopneumonia, nasal septal necrosis, fever, chills, malaise, headaches, pustular rash, lymphadenopathy, splenomegaly; chronic disease is associated with hepatosplenomegaly, pulmonary abscess, granulomas Treatment Sulfadiazine, tetracycline, chloramphenicol, aminoglycosides. See Farcy.