The dose of Sanchitongshu was 200 mg three times daily (standardised to ginsenoside
Rg1 50%, ginsenoside
Re 6%, notoginsenoside R1 11%).
These effects are distinct from those of Asian ginseng, and suggest that psychopharmacological properties depend critically on ginsenoside
profiles," said Andrew Scholey, Ph.
The effect of different ginsenoside
concentrations on physical work capacity.
The effects are distinct from those of Asian ginseng, and suggest that psychopharmacological properties depend on the plant's ginsenoside
profiles, said Andrew Scholey Ph.
They found that the complex structure of saponins, a type of ginsenoside
, may change chemically when they are processed, which in turn may modify their properties and activity.
For example, ginsenoside
from Panax gingseng, rosmarinic acid from Coleus blumei, shikonin from Lithospermum erythrohizon, diosgenin from Dioscorea, ubiquinone-10 from Nicotiana tabacum, berberin from Coptis japonica, and podophyllotoxin from Juniperus chinensis all accumulated at much higher levels in cultured cells than in intact plants (Misawa et al.
Rg3, the main component of ginseng, and cyclophosphamide synergistically acted to inhibit VEGF expression and micro-vessel density in human ovarian cancer in athymic mice (Xu et al.
Experts at the Chinese University of Hong Kong found ginsenoside
Rb1 was the culprit.
In fact, studies show that the less glucose a ginsenoside
contains, the more potent its activity is against cancers.
To determine what substance is responsible for the extract's effects, the researchers injected one berry ingredient, ginsenoside
Re, into obese, insulin-resistant mice.
Ginseng and ginsenoside
have been reported to regulate membrane [Ca.
While Western medical authorities are quick to point out that most of these claims are undocumented, the ginseng root does apparently produce a chemical called ginsenoside
that can boost absorption of protein, fat and sugar.