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giant-cell tumor

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giant-cell tumor
1. a rare bone tumor of dogs and cats with benign and malignant variants arising from primitive stromal elements of the bone marrow, composed of a spindle cell stroma containing multinucleated giant cells resembling osteoclasts.
2. carcinoma of the thyroid, a highly malignant undifferentiated neoplasm derived from poorly differentiated thyroid follicular cells.
3. giant cell epulis. See peripheral giant cell reparative granuloma.


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Facial lesions with histologic features of a giant-cell tumor should be evaluated from a systemic standpoint.
nbsp;are similar to those of giant-cell tumors except that they are usually related to pre-existing trauma.
 
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