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giant platelet

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giant platelet
A platetet that is larger than usual, a finding typical of Bernard-Soulier syndrome–BSS; up to 10% of normal platelets are 'giant', ie 'squashed' and oversized; when > 20% of platelets are giant, other conditions must be considered in addition to BSS–eg, ITP, lympho- and myeloproliferative disorders, reticulocytosis, DIC, SLE, gray platelet syndrome, May-Hegglin anomaly, Montreal platelet syndrome, TTP


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A giant platelet is defined as a platelet larger than a red cell (typically > 100 fL) but we know that particles >35 fL may impact the WBC count.
In addition, the giant platelets are not counted as "platelets" by these instruments.
 
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