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giant cell tumor of tendon sheath

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giant cell tumor of tendon sheath
n.
A nodule, possibly inflammatory, that usually develops from the flexor sheath of the fingers and thumb and is composed of fibrous tissue, multinucleated giant cells, and lipid- and hemosiderin-containing macrophages. Also called localized nodular tenosynovitis.

giant cell tumor of tendon sheath
Soft tissue tumors A potentially recurring lesion of the acral flexor tendon sheath which affects young Pts, is slightly more common in ♂, often with a long Hx, most common in the knee and ankle; GTTS is a variant of fibrous histiocytoma; it reaches a maximum of 3 mm, and may erode into bone. See Malignant giant cell tumor of tendon sheath.


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Giant cell tumor of tendon sheath frequently occurs in the fingers; some cases are extensively collagenized and may pose morphologic difficulties to the differential diagnosis with sclerosing perineurioma.
 
 
 
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