giant cell tumor of bone

A sometimes malignant osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells. It occurs most frequently in an end of a long tubular bone. Also called giant cell myeloma, osteoclastoma.

giant cell tumor of bone.

See giant cell myeloma.

A lesion that comprises 5% of all osseous tumors, which is most common in the weight-bearing epiphysis of ♀ > age 20, which affects the distal femur, proximal tibia, distal radius; 60% recur with curettage; 10% metastasize, an event far more common in deep–to the fascial planes–tumors DiffDx A GCT-like histopathologic lesion may be seen in the brown tumor of hyperparathyroidism, chondroblastoma, giant cell reparative granuloma, benign and malignant fibrous histiocytoma, nonossifying and chondromyxoid fibroma, unicameral bone cyst, aneurysmal bone cyst, fibrous dysplasia, osteoblastoma, osteosarcoma, osteoid osteoma, eosinophilic granuloma

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alveolar soft part sarcoma ameloblastic sarcoma botryoid sarcoma endometrial stromal sarcoma Ewing's sarcoma giant cell myeloma giant cell sarcoma Kaposi sarcoma osteoclastoma osteogenic sarcoma pseudo-Kaposi sarcoma reticulum cell sarcoma Rous sarcoma sarcoma soft tissue sarcoma	Expression of Ia and monocyte-macrophage lineage antigens in giant cell tumor of bone and related lesions. PET/CT-positive brown tumour--a potentially misleading finding in the ... by Makhzomi, M. Al-; Sathekge, M.; Seynaeve, P.; Nicolaij, D.; Maes, A. / South African Journal of Radiology [4] Giant cell tumor of bone is believed to be of monocytic or histiocytic origin, and the presence of giant cells is attributed to fusion of the mononuclear cells. An Unusual Salivary Gland Tumor by Snyder, Matthew L.; Paulino, Augusto F. G. / Archives of Pathology & Laboratory Medicine Giant cell tumor of bone is rich in RANK Ligand positive cells, which results in giant osteoclasts that destroy the bone locally. Interim Phase 2 Results of Open-Label Clinical Trial of Denosumab in ... by Business Wire	GI Bleeding Studies GI series GI tract Gianotti-Crosti syndrome giant giant axonal neuropathy Giant Cavernous Hemangioma Giant Cell giant cell arteritis Giant Cell Bone Tumour of Bone Giant Cell Bone Tumour of Tendon Sheath giant cell carcinoma Giant Cell Fibroblastoma Giant Cell Fibroma Giant Cell Glioblastoma Giant Cell Granuloma Giant Cell Hepatitis Giant Cell Interstitial Pneumonia giant cell myeloma Giant Cell Myocarditis Giant Cell Pneumonia Giant Cell Reaction Giant Cell Reparative Granuloma giant cell sarcoma giant cell thyroiditis giant cell tumor of bone giant cell tumor of tendon sheath giant chromosome giant condyloma giant condyloma acuminatum Giant Condyloma Acuminatum of Büschke-Loewenstein giant follicular lymphoma giant hemangioma of Kasabach-Merritt giant hypertrophic gastritis Giant Metamyelocyte Giant Mitochondria Giant Peristaltic Contraction Giant Pigmented Hairy Nevus Giant Platelet giant platelet syndrome Giant Sets Giant T Wave Inversion giant urticaria giant-cell tumor giantism giantophthalmos Gianturco coil Giardia Giardia lamblia giardiasis gibata	giant cell granuloma giant cell hepatitis giant cell interstitial pneumonia giant cell interstitial pneumonia giant cell interstitial pneumonia giant cell interstitial pneumonia giant cell myeloma giant cell myeloma giant cell myeloma giant cell myocarditis giant cell myocarditis giant cell myocarditis giant cell pneumonia giant cell reaction giant cell reparative granuloma giant cell reparative granuloma giant cell reparative granuloma giant cell reparative granuloma giant cell reparative granuloma, central giant cell reparative granuloma, central giant cell reparative granuloma, central giant cell sarcoma giant cell sarcoma giant cell sarcoma giant cell thyroiditis Giant cell transformation of liver giant cell tumor giant cell tumor giant cell tumor giant cell tumor giant cell tumor of bone giant cell tumor of tendon sheath giant cell tumor of tendon sheath Giant cells Giant cells Giant cells Giant Cells of Foreign Bodies Giant cells, langhans Giant cells, langhans Giant Cement Holding, Inc. Giant Cerebriform Intradermal Nevus giant chinkapin giant chinquapin giant chromosome Giant City State Park giant clam giant clam giant clams giant clams Giant Cloud Condensation Nuclei Giant club moss Giant club moss Giant club mosses Giant club mosses Giant clubmoss Giant clubmoss Giant clubmosses Giant clubmosses giant cockroach giant conch giant condyloma

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alveolar soft part sarcoma
ameloblastic sarcoma
botryoid sarcoma
endometrial stromal sarcoma
Ewing's sarcoma
giant cell myeloma
giant cell sarcoma
Kaposi sarcoma
osteoclastoma
osteogenic sarcoma
pseudo-Kaposi sarcoma
reticulum cell sarcoma
Rous sarcoma
sarcoma
soft tissue sarcoma

Expression of Ia and monocyte-macrophage lineage antigens in giant cell tumor of bone and related lesions.

PET/CT-positive brown tumour--a potentially misleading finding in the ... by Makhzomi, M. Al-; Sathekge, M.; Seynaeve, P.; Nicolaij, D.; Maes, A. / South African Journal of Radiology

[4] Giant cell tumor of bone is believed to be of monocytic or histiocytic origin, and the presence of giant cells is attributed to fusion of the mononuclear cells.

An Unusual Salivary Gland Tumor by Snyder, Matthew L.; Paulino, Augusto F. G. / Archives of Pathology & Laboratory Medicine

Giant cell tumor of bone is rich in RANK Ligand positive cells, which results in giant osteoclasts that destroy the bone locally.

Interim Phase 2 Results of Open-Label Clinical Trial of Denosumab in ... by Business Wire

GI Bleeding Studies

GI series

GI tract

Gianotti-Crosti syndrome

giant

giant axonal neuropathy

Giant Cavernous Hemangioma

Giant Cell

giant cell arteritis