giant cell granuloma

gi·ant cell gran·u·lo·ma

a nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs in the gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency; microscopically similar lesions occur in the tubular bones of the hands and feet, are considered neoplastic and may have a malignant course. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone.
(1) Central giant cell granuloma
(2) Peripheral giant cell granuloma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă)
A nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs on the gingiva and alveolar mucosa (occasionally on other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone
Compare: giant cell fibroma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă)
Nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; occurs in gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency.
References in periodicals archive ?
5,6) The differential diagnosis should include hemangioma, bacillary angiomatosis, peripheral giant cell granuloma, peripheral ossifying fibroma, and some malignancies, such as Kaposi sarcoma, squamous cell carcinoma, and achromic melanoma.
The preoperative diagnosis consisted of traumatic bone cyst, central giant cell granuloma, or ameloblastoma.
The World Health Organisation (2005) define a central giant cell granuloma as a benign intraosseous lesion consisting of fibrous tissue containing foci of haemorrhage and haemosiderin deposits, aggregations of giant cells and reactive bone formation.
The patient was diagnosed as WG because a giant cell granuloma and necrotizing leucocytoclastic vasculitis were observed on the pathologic examination of the biopsy specimens obtained from these lesions.
Annular elastolytic giant cell granuloma causes an irreversible disappearance of the elastic fibres.
The clinical differential diagnosis in conjunction with radiographic findings in this patient initially included non-odontogenic primary tumors of bone, such as osteoblastoma, aneurysmal bone cyst, central giant cell granuloma, osteogenic sarcoma, progressive monostotic fibrous dysplasia (FD), and juvenile OF.
Giant-cell-containing lesions of the jaw that can be mistaken for each other histologically include GCT, giant cell granuloma, cherubism, and fibrous dysplasia of the jaw.
The nodule was excised and submitted for histologic analysis with the differential diagnosis of pyogenic granuloma, peripheral ossifying fibroma, peripheral giant cell granuloma, or traumatic fibroma.
Central giant cell granuloma (CGCG) is a benign but locally destructive lesion of the mandible or maxilla that presents most often in the second and third decades of life.
We examined a young man who had a benign giant cell granuloma of the maxilla, which we subsequently diagnosed as a brown tumor associated with hyperparathyroidism.

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