giant cell granuloma

gi·ant cell gran·u·lo·ma

a nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs in the gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency; microscopically similar lesions occur in the tubular bones of the hands and feet, are considered neoplastic and may have a malignant course. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone.
(1) Central giant cell granuloma
(2) Peripheral giant cell granuloma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă)
A nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs on the gingiva and alveolar mucosa (occasionally on other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone
Compare: giant cell fibroma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă)
Nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; occurs in gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency.
References in periodicals archive ?
This provides differentiation from additional entities that typically include giant cells: cherubism, central giant cell granuloma, giant cell tumor in the setting of paget's disease, and aneurysmal bone cyst.
ABC occurs in two clinicopathological forms as a primary (de novo) or as a secondary lesion arising from another osseous condition, which includes giant cell granuloma, ossifying fibroma, and fibrous dysplasia.
The differential diagnosis includes peripheral ossifying fibroma, peripheral giant cell granuloma, granulation tissue, Kaposi sarcoma, and angiosarcoma.
Differential diagnosis includes peripheral odontogenic fibroma, pyogenic granuloma, peripheral giant cell granuloma, peripheral ameloblastoma, and calcifying epithelial odontogenic tumor.
24 One patient with jaw mass had a giant cell granuloma, which is rarely seen as a sole manifestation of PHPT.
Many of these lesions can be identified as specific entities on the basis of their histopathological features and are divided into irritational fibroma, epulis fissuratum, squamous papilloma, giant cell fibroma, pyogenic granuloma and peripheral giant cell granuloma.
As a result of the examination the patient was sent for an operation with preliminary diagnoses of reparative giant cell granuloma epulis fissuratum and condyloma accuminatum.
The preoperative diagnosis consisted of traumatic bone cyst, central giant cell granuloma, or ameloblastoma.
Central Giant Cell Granuloma is a benign proliferative lesion common seen in young females, typically occurs anterior to the first molar & often crosses the midline.
Growth potential of peripheral giant cell granuloma.
The World Health Organisation (2005) define a central giant cell granuloma as a benign intraosseous lesion consisting of fibrous tissue containing foci of haemorrhage and haemosiderin deposits, aggregations of giant cells and reactive bone formation.
21) In fact, myofibroblasts have also been sporadically detected in central giant cell granuloma, (29) a lesion histologically similar to PGCG.

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