germ cells


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Related to germ cells: Primordial germ cells

germ cells

Sexual reproductive cells. See OVA and SPERMATOZOA.
References in periodicals archive ?
The use of immunohistochemical stains is imperative in the diagnosis of germ cell tumours.
Risk factors for testicular cancer include cryptorchidism (testicular maldescent), carcinoma in situ (intratubular germ cell neoplasia), history of testicular cancer or extragonadal germ cell tumor, family history, HIV infection, Down syndrome, and testicular trauma.
Similarly, overexpression of GDNF and its mRNA has been reported following busulfan treatment, the drug which eliminates germ cells from seminiferous tubules in mice (19-21).
Management of malignant germ cell neoplasms generally includes fertility-sparing surgery--with or without neoadjuvant combination bleomycin, etoposide, and cisplatin (BEP)--and is typically associated with a favorable prognosis (Cancer Treat Rev.
Ovarian germ cell tumors occur at a relatively early stage; stage I (75%) and only few cases occur at stage IV (5%) (3).
Recently, a panel of reproductive biologists proposed gold standard criteria to prove that the major events of meiosis have taken place in engineered germ cells.
In a study of the blue mussel (Mytilus galloprovincialis), proliferation and migration of immature germ cells was observed by in situ hybridization (ISH) using the vasa ortholog (Myvlg) (Obata et al.
Demographic and clinical data, including IGCCCG (International Germ Cell Classification Collaborative Group) classification, treatment details, and clinical outcomes, were extracted from the database and original medical records as necessary.
The results suggest that germ cells have developed a strong system for ensuring that epigenetic information doesn't sneak through to subsequent generations.
2) A new study in EHP provides new evidence regarding mechanisms of DBP-related effects in germ cells and suggests that a rat model may be suitable for studying effects of DBP on human germ cells.
Exact origin of melanoma in GCTs is unknown but these may occur from transformation of dermal elements or de-differentiation of germ cells to melanomas.