genotoxin


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Related to genotoxin: genotoxic carcinogen

genotoxin

(gē-nō-tok'sin),
Any substance that damage DNA.

genotoxin

(jē′nə-tŏk′sĭn)
n.
A chemical or other agent that damages cellular DNA, resulting in mutations or cancer.

ge′no·tox′ic adj.
ge′no·tox·ic′i·ty (-sĭs′ĭ-tē) n.

genotoxin

a chemical or other agent that damages cellular DNA resulting for example in MUTATIONS or CANCER.
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References in periodicals archive ?
53] tumor suppressor gene, which is known to be implicated in cancer development, has been investigated as a possible biomarker for genotoxin in fish cells [134].
Neither of these solvents is considered a genotoxin or a carcinogen; the weight of evidence from human in vivo studies suggests that exposure to toluene does not cause somatic cell genotoxic damage (7), although this view has been questioned by recent studies of rotogravure printers (8,9).
In addition to bacterial assays, MX is a direct-acting mutagen and genotoxin in vivo (17-21) and in mammalian cells in vitro (21-27).
Transplacental transfer of genotoxins and transplacental carcinogenesis.
Blair, "Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins," Science, vol.
Since presence of genotoxins in the aquatic environment is a well-known fact, attempt to develop sensitive biomarkers to evaluate genotoxic effects in aquatic organisms has gained importance.
Potentially harmful constituents have been documented in some e-cigarette cartridges, including diethylene glycol, genotoxins and animal carcinogen," it added.
Potentially harmful constituents also have been documented in some e-cigarette cartridges, including irritants, genotoxins, and animal carcinogens (1).
BlueScreen HC uses Gaussia luciferase to detect the up-regulation of a key reporter gene, GADD-45a, in response to genotoxic stress and can detect all known classes of genotoxins.
Nevertheless in the study cited above (1) the intensity of exposure to genotoxins from polluted air was able to induce chromosomal damage more efficiently than tobacco smoke.